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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $121 | 5 days |
Description | DBCO-PEG1-NHS ester is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands necessary for PROTAC molecule formation. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, containing two ligands connected by a linker—one for an E3 ubiquitin ligase and the other for the target protein—leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 517.53 |
Formula | C28H27N3O7 |
Cas No. | 2228857-34-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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