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Kallikrein 8/KLK8 Protein, Human, Recombinant (aa 29-260, His)

Catalog No. TMPJ-00557
Synonyms: Tumor-Associated Differentially Expressed Gene 14 Protein, TADG14, NP, Kallikrein-8, Serine Protease 19, hK8, PRSS19, Serine Protease TADG-14, NRPN, Ovasin, Neuropsin, KLK8

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.

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Kallikrein 8/KLK8 Protein, Human, Recombinant (aa 29-260, His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 545.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
Species Human
Expression System Human Cells
Tag C-6His
Accession Number AAH40887.1
Synonyms Tumor-Associated Differentially Expressed Gene 14 Protein, TADG14, NP, Kallikrein-8, Serine Protease 19, hK8, PRSS19, Serine Protease TADG-14, NRPN, Ovasin, Neuropsin, KLK8
Amino Acid Gln29-GLy260
Construction Recombinant Human Kallikrein 8 is produced by our Mammalian expression system and the target gene encoding Gln29-GLy260 is expressed with a 6His tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 35 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Stability & Storage

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Shipping

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Research Background Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.

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Keywords

Kallikrein 8/KLK8 Protein, Human, Recombinant (aa 29-260, His) PRSS-19 Tumor-Associated Differentially Expressed Gene 14 Protein PRSS 19 TADG14 TADG 14 NP Kallikrein-8 Serine Protease 19 hK8 PRSS19 Serine Protease TADG-14 KLK 8 KLK-8 NRPN TADG-14 Ovasin Neuropsin KLK8 recombinant recombinant-proteins proteins protein

 

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