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Patchouli alcohol

🥰Excellent
Catalog No. T2916Cas No. 5986-55-0
Alias Patchoulol, Patchouli camphor, (-)-Patchouli Alcohol

Patchouli alcohol (Patchoulol) is a naturally occurring tricyclic sesquiterpenoid found in patchouli oil. It is a key bioactive component known for its immunomodulatory, anti-inflammatory, antioxidant, antitumor, antibacterial, anti-atherosclerotic, antiemetic, and sedative properties.

Patchouli alcohol

Patchouli alcohol

🥰Excellent
Purity: 99.3%
Catalog No. T2916Alias Patchoulol, Patchouli camphor, (-)-Patchouli AlcoholCas No. 5986-55-0
Patchouli alcohol (Patchoulol) is a naturally occurring tricyclic sesquiterpenoid found in patchouli oil. It is a key bioactive component known for its immunomodulatory, anti-inflammatory, antioxidant, antitumor, antibacterial, anti-atherosclerotic, antiemetic, and sedative properties.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$30In StockIn Stock
25 mg$50In StockIn Stock
50 mg$70In StockIn Stock
100 mg$100In StockIn Stock
200 mg$145In StockIn Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.3%
Color:White
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Product Introduction

Bioactivity
Description
Patchouli alcohol (Patchoulol) is a naturally occurring tricyclic sesquiterpenoid found in patchouli oil. It is a key bioactive component known for its immunomodulatory, anti-inflammatory, antioxidant, antitumor, antibacterial, anti-atherosclerotic, antiemetic, and sedative properties.
In vitro
METHODS: H. pylori-infected GES-1 cells were treated with Patchouli alcohol (5-20 µg/mL) for 24 h. Apoptosis was detected by flow cytometry.
RESULTS: Patchouli alcohol treatment significantly reduced H. pylori-induced apoptosis. [1]
METHODS: H. pylori-infected GES-1 cells were treated with Patchouli alcohol (5-20 µg/mL) for 24 h, and cytokine levels were measured by ELISA.
RESULTS: 5-20 µg/mL Patchouli alcohol treatment significantly reduced the production of TNF-α and MCP-1. [1]
In vivo
METHODS: To study the effect on H. pylori-associated gastritis, Patchouli alcohol (5-20 mg/kg) was administered orally to H. pylori-infected mice once daily for two weeks.
RESULTS: Patchouli alcohol treatment increased SH-NP content and CAT activity, and significantly protected the gastric mucosa from H. pylori-induced damage. [1]
SynonymsPatchoulol, Patchouli camphor, (-)-Patchouli Alcohol
Chemical Properties
Molecular Weight222.37
FormulaC15H26O
Cas No.5986-55-0
Smiles[H][C@@]12CC[C@@]3(C)[C@]([H])(C1)[C@@H](C)CC[C@@]3(O)C2(C)C
Relative Density.1.001 g/cm3
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 45 mg/mL (202.37 mM), Sonication is recommended.
Ethanol: 15 mg/mL (67.46 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (22.49 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM4.4970 mL22.4850 mL44.9701 mL224.8505 mL
5 mM0.8994 mL4.4970 mL8.9940 mL44.9701 mL
10 mM0.4497 mL2.2485 mL4.4970 mL22.4850 mL
20 mM0.2249 mL1.1243 mL2.2485 mL11.2425 mL
50 mM0.0899 mL0.4497 mL0.8994 mL4.4970 mL
DMSO
1mg5mg10mg50mg
100 mM0.0450 mL0.2249 mL0.4497 mL2.2485 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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