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L-Homopropargylglycine hydrochloride

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Catalog No. T41089Cas No. 942518-19-6
Alias L-Homopropargylglycine HCl

L-Homopropargylglycine hydrochloride is an alkyl-chain PROTAC linker suitable for synthesising PROTAC molecules. L-Homopropargylglycine hydrochloride contains an alkyne moiety capable of undergoing click chemistry reactions with azide-containing compounds.

L-Homopropargylglycine hydrochloride
Other Forms of L-Homopropargylglycine hydrochloride:
L-HomopropargylglycineT1569498891-36-2
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L-Homopropargylglycine hydrochloride

🥰Excellent
Catalog No. T41089Alias L-Homopropargylglycine HClCas No. 942518-19-6
L-Homopropargylglycine hydrochloride is an alkyl-chain PROTAC linker suitable for synthesising PROTAC molecules. L-Homopropargylglycine hydrochloride contains an alkyne moiety capable of undergoing click chemistry reactions with azide-containing compounds.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$30-In Stock
10 mg$50-In Stock
25 mg$98-In Stock
50 mg$172-In Stock
100 mg$255-In Stock
200 mg$378-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
L-Homopropargylglycine hydrochloride is an alkyl-chain PROTAC linker suitable for synthesising PROTAC molecules. L-Homopropargylglycine hydrochloride contains an alkyne moiety capable of undergoing click chemistry reactions with azide-containing compounds.
In vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
SynonymsL-Homopropargylglycine HCl
Chemical Properties
Molecular Weight163.6
FormulaC6H10ClNO2
Cas No.942518-19-6
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 80 mg/mL (489 mM), Sonication is recommended.
DMSO: 100 mg/mL (611.25 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM6.1125 mL30.5623 mL61.1247 mL305.6235 mL
5 mM1.2225 mL6.1125 mL12.2249 mL61.1247 mL
10 mM0.6112 mL3.0562 mL6.1125 mL30.5623 mL
20 mM0.3056 mL1.5281 mL3.0562 mL15.2812 mL
50 mM0.1222 mL0.6112 mL1.2225 mL6.1125 mL
100 mM0.0611 mL0.3056 mL0.6112 mL3.0562 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

L-Homopropargylglycine HydrochlorideLHomopropargylglycine hydrochlorideL Homopropargylglycine hydrochloride
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