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BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated
(Synonyms: ZTNF4, Tumor necrosis factor ligand superfamily member 13B, TNFSF20, TNFSF13B, TNF- and APOL-related leukocyte expressed ligand 1, TALL-1, Dendritic cell-derived TNF-like molecule, CD257, BLyS, B-cell-activating factor, BAFF, B lymphocyte stimulator) Copy Product InfoSynonyms: ZTNF4, Tumor necrosis factor ligand superfamily member 13B, TNFSF20, TNFSF13B, TNF- and APOL-related leukocyte expressed ligand 1, TALL-1, Dendritic cell-derived TNF-like molecule, CD257, BLyS, B-cell-activating factor, BAFF, B lymphocyte stimulator
Catalog No. TMPJ-00177 Copy Product Info
B-cell activating factor (BAFF), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a transmembrane glycoprotein in the TNF ligand superfamily. BAFF is a cytokine and serves as a ligand for receptors TNFRSF13B (TACI), TNFRSF17 (BCMA), and TNFRSF13C (BAFFR). BAFF can promotes the survival, proliferation and maturation of B lymphocytes, which are key elements in the pathogenesis of systemic lupus erythematosus (SLE). This cytokine is encoded on TNFSF13B gene, and diverse single-nucleotide polymorphisms have been associated with susceptibility in diferent autoimmune disorders. BAFF is a transmembranal protein expressed on myeloid lineage and some epithelial cells, through diferent stimuli such as IFN-γ, IFN-α, interleukin (IL)-10, Toll-like receptors (TLR)-3, TLR-4 and TLR-7.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $129 | 7-10 days | 7-10 days | |
| 10 μg | $213 | 7-10 days | 7-10 days | |
| 20 μg | $355 | 7-10 days | 7-10 days | |
| 50 μg | $625 | 7-10 days | 7-10 days | |
| 100 μg | $963 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Recombinant Human BCMA-His-Flag at 5μg/ml (100 μl/well)can bind Biotinylated Human BAFF-Avi-Fc. The ED50 of Biotinylated Human BAFF-Avi-Fc is 29.46 ng/ml. (Regularly tested) |
| Description | B-cell activating factor (BAFF), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a transmembrane glycoprotein in the TNF ligand superfamily. BAFF is a cytokine and serves as a ligand for receptors TNFRSF13B (TACI), TNFRSF17 (BCMA), and TNFRSF13C (BAFFR). BAFF can promotes the survival, proliferation and maturation of B lymphocytes, which are key elements in the pathogenesis of systemic lupus erythematosus (SLE). This cytokine is encoded on TNFSF13B gene, and diverse single-nucleotide polymorphisms have been associated with susceptibility in diferent autoimmune disorders. BAFF is a transmembranal protein expressed on myeloid lineage and some epithelial cells, through diferent stimuli such as IFN-γ, IFN-α, interleukin (IL)-10, Toll-like receptors (TLR)-3, TLR-4 and TLR-7. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | N-Avi-Fc |
| Accession Number | Q9Y275 |
| Amino Acid | Ala134-Leu285 |
| Construction | Ala134-Leu285 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | ZTNF4, Tumor necrosis factor ligand superfamily member 13B, TNFSF20, TNFSF13B, TNF- and APOL-related leukocyte expressed ligand 1, TALL-1, Dendritic cell-derived TNF-like molecule, CD257, BLyS, B-cell-activating factor, BAFF, B lymphocyte stimulator |
| Research Background |
| Molecular Weight | 50-60 KDa (reducing condition) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Related Tags: BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated chemical structure | BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated molecular weight
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