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Anti-GPHA2 Antibody (7J791)
😃Good
Catalog No. TMAY-02652
Alias ZSIG51, GPA2, glycoprotein hormone α 2, glycoprotein hormone alpha 2, A2
Anti-GPHA2 Antibody (7J791) is a Mouse antibody targeting GPHA2. Anti-GPHA2 Antibody (7J791) can be used in ELISA.
Anti-GPHA2 Antibody (7J791)
Anti-GPHA2 Antibody (7J791)
😃Good
Catalog No. TMAY-02652Alias ZSIG51, GPA2, glycoprotein hormone α 2, glycoprotein hormone alpha 2, A2
Anti-GPHA2 Antibody (7J791) is a Mouse antibody targeting GPHA2. Anti-GPHA2 Antibody (7J791) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA Reactivity: Human |
| Alias | ZSIG51, GPA2, glycoprotein hormone α 2, glycoprotein hormone alpha 2, A2 |
| Ig Type | Mouse IgG1 |
| Clone | 7J791 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GPHA2 / glycoprotein hormone alpha 2 (rh GPHA2 / glycoprotein hormone alpha 2; TMPY-03784; Q96T91; Met1-Tyr129). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | GPHA2 is a member of the glycoprotein hormones subunit alpha family. Glycoprotein hormones consist of two subunits, the common alpha- and specific beta-subunits, which associate noncovalently to form a heterodimer. The alpha-subunit combines with four distinct beta-subunits giving rise to four biologically active hormones in the human: FSH, LH, TSH, and CG. GPHA2 and glycoprotein hormone beta 5 (GPHB5) can form a noncovalent heterodimer. GPHA2 can be detected in a variety of tissues. Recombinant A2/B5 heterodimeric glycoproteins activate human TSH receptors, but not LH and FSH receptors, and shows high affinity to TSH receptors in a radioligand receptor assay. The heterodimer also stimulates cAMP production and thymidine incorporation by cultured thyroid cells and increases serum thyroxine levels in TSH-suppressed rats in vivo. This new heterodimeric glycoprotein hormone was named Thyrostimulin based on its thyroid-stimulating activity. The expression of Thyrostimulin in the anterior pituitary known to express TSH receptors suggested a paracrine mechanism. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human GPHA2 / glycoprotein hormone alpha 2 Protein (TMPY-03784) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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