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Anti-GPHA2 Antibody (7J791)

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Catalog No. TMAY-02652
Alias ZSIG51, GPA2, glycoprotein hormone α 2, glycoprotein hormone alpha 2, A2

Anti-GPHA2 Antibody (7J791) is a Mouse antibody targeting GPHA2. Anti-GPHA2 Antibody (7J791) can be used in ELISA.

Anti-GPHA2 Antibody (7J791)

Anti-GPHA2 Antibody (7J791)

😃Good
Catalog No. TMAY-02652Alias ZSIG51, GPA2, glycoprotein hormone α 2, glycoprotein hormone alpha 2, A2
Anti-GPHA2 Antibody (7J791) is a Mouse antibody targeting GPHA2. Anti-GPHA2 Antibody (7J791) can be used in ELISA.
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100 μL$199 7-10 days
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Product Introduction

Bioactivity
Description
Anti-GPHA2 Antibody (7J791) is a Mouse antibody targeting GPHA2. Anti-GPHA2 Antibody (7J791) can be used in ELISA.
AliasZSIG51, GPA2, glycoprotein hormone α 2, glycoprotein hormone alpha 2, A2
Ig Type
Monoclonal Mouse IgG1
Clone
7J791
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GPHA2 / glycoprotein hormone alpha 2 (rh GPHA2 / glycoprotein hormone alpha 2; TMPY-03784; Q96T91; Met1-Tyr129). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundGPHA2 is a member of the glycoprotein hormones subunit alpha family. Glycoprotein hormones consist of two subunits, the common alpha- and specific beta-subunits, which associate noncovalently to form a heterodimer. The alpha-subunit combines with four distinct beta-subunits giving rise to four biologically active hormones in the human: FSH, LH, TSH, and CG. GPHA2 and glycoprotein hormone beta 5 (GPHB5) can form a noncovalent heterodimer. GPHA2 can be detected in a variety of tissues. Recombinant A2/B5 heterodimeric glycoproteins activate human TSH receptors, but not LH and FSH receptors, and shows high affinity to TSH receptors in a radioligand receptor assay. The heterodimer also stimulates cAMP production and thymidine incorporation by cultured thyroid cells and increases serum thyroxine levels in TSH-suppressed rats in vivo. This new heterodimeric glycoprotein hormone was named Thyrostimulin based on its thyroid-stimulating activity. The expression of Thyrostimulin in the anterior pituitary known to express TSH receptors suggested a paracrine mechanism.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human GPHA2 / glycoprotein hormone alpha 2 Protein (TMPY-03784)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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