Thymopentin is a member of the LEM family. Thymopentin is expressed in many tissues, highly in the adult thymus and fetal liver. The N-terminal contains two structurally independent domains, LEM domain and LEM-like domain. The C-terminal domain forms a four-stranded coiled coil. Thymopentin may be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. It is associated with T-cell development and function. Meantime, Thymopentin plays an important role, together with LMNA, in the nuclear anchorage of RB1. Thymopoietin is participated in the induction of CD90 in the thymus.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 μg | 5 days | $ 129.00 | |
50 μg | 5 days | $ 390.00 | |
500 μg | 5 days | $ 1,900.00 | |
1 mg | 5 days | $ 2,730.00 |
Description | Thymopentin is a member of the LEM family. Thymopentin is expressed in many tissues, highly in the adult thymus and fetal liver. The N-terminal contains two structurally independent domains, LEM domain and LEM-like domain. The C-terminal domain forms a four-stranded coiled coil. Thymopentin may be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. It is associated with T-cell development and function. Meantime, Thymopentin plays an important role, together with LMNA, in the nuclear anchorage of RB1. Thymopoietin is participated in the induction of CD90 in the thymus. |
Species | Human |
Expression System | E. coli |
Tag | C-6His |
Accession Number | P42167 |
Synonyms | Thymopoietin-Related Peptide Isoforms β/γ, Splenin, TMPO, TP, TP5, LAP2, Lamina-Associated Polypeptide 2 Isoforms Beta/Gamma, TPRP Isoforms β/γ, Thymopentin, Thymopoietin-Related Peptide Isoforms Beta/Gamma, Thymopoietin Isoforms Beta/Gamma, TP β/γ, TP Beta/γ, Lamina-Associated Polypeptide 2 Isoforms β/γ, Thymopoietin, TPRP Isoforms Beta/Gamma, Thymopoietin Isoforms β/γ, TP Beta/Gamma |
Amino Acid | Met1-Glu187 |
Construction | Recombinant Human Thymopoietin is produced by our E.coli expression system and the target gene encoding Met1-Glu187 is expressed with a 6His tag at the C-terminus. |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
Molecular Weight | 27 KDa, reducing conditions |
Endotoxin | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Stability & Storage |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
Shipping |
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Research Background | Thymopentin is a member of the LEM family. Thymopentin is expressed in many tissues, highly in the adult thymus and fetal liver. The N-terminal contains two structurally independent domains, LEM domain and LEM-like domain. The C-terminal domain forms a four-stranded coiled coil. Thymopentin may be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. It is associated with T-cell development and function. Meantime, Thymopentin plays an important role, together with LMNA, in the nuclear anchorage of RB1. Thymopoietin is participated in the induction of CD90 in the thymus. |
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Please read the User Guide of Recombinant Proteins for more specific information.
TMPO Protein, Human, Recombinant (His) LAP-2 Thymopoietin-Related Peptide Isoforms β/γ Splenin TP-5 TMPO TP TP5 LAP2 Lamina-Associated Polypeptide 2 Isoforms Beta/Gamma TPRP Isoforms β/γ Thymopentin Thymopoietin-Related Peptide Isoforms Beta/Gamma TP 5 LAP 2 Thymopoietin Isoforms Beta/Gamma TP β/γ TP Beta/γ Lamina-Associated Polypeptide 2 Isoforms β/γ Thymopoietin TPRP Isoforms Beta/Gamma Thymopoietin Isoforms β/γ TP Beta/Gamma recombinant recombinant-proteins proteins protein