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Anti-PTGES3 Antibody (3N840)
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Catalog No. TMAC-02944
Alias Telomerase-binding protein p23, TEBP, PTGES3, Prostaglandin E synthase 3, Progesterone receptor complex p23, P23, Hsp90 co-chaperone, Cytosolic prostaglandin E2 synthase (cPGES)
Anti-PTGES3 Antibody (3N840) is a Rabbit antibody targeting PTGES3. Anti-PTGES3 Antibody (3N840) can be used in ICC,IHC,IP,WB.
Anti-PTGES3 Antibody (3N840)
Anti-PTGES3 Antibody (3N840)
😃Good
Catalog No. TMAC-02944Alias Telomerase-binding protein p23, TEBP, PTGES3, Prostaglandin E synthase 3, Progesterone receptor complex p23, P23, Hsp90 co-chaperone, Cytosolic prostaglandin E2 synthase (cPGES)
Anti-PTGES3 Antibody (3N840) is a Rabbit antibody targeting PTGES3. Anti-PTGES3 Antibody (3N840) can be used in ICC,IHC,IP,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $296 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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| Description | Anti-PTGES3 Antibody (3N840) is a Rabbit antibody targeting PTGES3. Anti-PTGES3 Antibody (3N840) can be used in ICC,IHC,IP,WB. |
| Synonyms | Telomerase-binding protein p23, TEBP, PTGES3, Prostaglandin E synthase 3, Progesterone receptor complex p23, P23, Hsp90 co-chaperone, Cytosolic prostaglandin E2 synthase (cPGES) |
| Ig Type | IgG |
| Clone | 3N840 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of p23 on different lysates using anti-p23 antibody at 1/500 dilution. Positive control: Lane 1: Mouse brain tissue, Lane 2: SK-Br-3, Lane 3: Rat lung tissue. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-p23 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-p23 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse fallopian tube tissue using anti-p23 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded rat testis tissue using anti-p23 antibody. Counter stained with hematoxylin. 6. ICC staining p23 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 7. ICC staining p23 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.        |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:100-500; ICC: 1:50-200; IP: 1:10-50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | P23, also known as PTGES3 (prostaglandin E synthase 3) or TEBP (telomerase-binding protein p23), is a ubiquitously expressed protein that functions as a cochaperone and plays an important role in signal transduction. One of several proteins in the HSP 90-based molecular chaperone complex, P23 promotes the breakdown of transcriptional regulatory complexes by disrupting receptor-mediated transcriptional activation. P23 acts in a hormone-dependent manner to chaperone estrogen receptor alpha (ERα), a steroid complex, to its mature form and to regulate the expression of ERα-related genes. Localized to the cytoplasm, P23 interacts with the glucocorticoid receptor (GR) and, through disassembly of the GR transcription machinery, is thought to inhibit GR-dependent transcription. The involvement of P23 in various steroid receptor-mediated pathways suggests close involvement in signal transduction and regulation of cellular processes. Upregulation of P23 is implicated in the invasion and metastasis of various cancers. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 23 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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