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Anti-Phospho-AurB/C (Thr236/202) Polyclonal Antibody (Synonyms: p-AurB/C (Thr236/202), p-AurB/C (T236/202), Au...)

Catalog No. TMAC-00348 Copy Product Info
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Anti-Phospho-AurB/C (Thr236/202) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AurB/C (Thr236/202). Anti-Phospho-AurB/C (Thr236/202) Polyclonal Antibody can be used in IHC.

Anti-Phospho-AurB/C (Thr236/202) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAC-00348
Synonyms p-AurB/C (Thr236/202), p-AurB/C (T236/202), AurB/C (p-Thr236/202), AurB/C (p-T236/202)

Anti-Phospho-AurB/C (Thr236/202) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AurB/C (Thr236/202). Anti-Phospho-AurB/C (Thr236/202) Polyclonal Antibody can be used in IHC.

Anti-Phospho-AurB/C
(Thr236/202) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2187-10 days7-10 days
100 μL$3167-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-AurB/C (Thr236/202) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AurB/C (Thr236/202). Anti-Phospho-AurB/C (Thr236/202) Polyclonal Antibody can be used in IHC.
Synonymsp-AurB/C (Thr236/202), p-AurB/C (T236/202), AurB/C (p-Thr236/202), AurB/C (p-T236/202)
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Immunohistochemistry analysis of paraffin-embedded human brain tissue using AurB/C (Phospho-Thr236/202) antibody TMAC-00348. The picture on the right is treated with the synthesized peptide.
verifiedActivity
Application
Recommended Dose
IHC: 1:50-100
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundSerine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at 'Ser-10' and 'Ser-28'. Phosphorylates TACC1, another protein involved in cell division, at 'Ser-228'.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of threonine 236/202 (C-G-T(p)-L-D) derived from Human AurB/C
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 35 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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