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Anti-Phospho-AurB/C (Thr236/202) Polyclonal Antibody
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Catalog No. TMAC-00348
Anti-Phospho-AurB/C (Thr236/202) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AurB/C (Thr236/202). Anti-Phospho-AurB/C (Thr236/202) Polyclonal Antibody can be used in IHC.
Anti-Phospho-AurB/C (Thr236/202) Polyclonal Antibody
Anti-Phospho-AurB/C (Thr236/202) Polyclonal Antibody
😃Good
Catalog No. TMAC-00348
Anti-Phospho-AurB/C (Thr236/202) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AurB/C (Thr236/202). Anti-Phospho-AurB/C (Thr236/202) Polyclonal Antibody can be used in IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $218 | 7-10 days | |
| 100 μL | $316 | 7-10 days |
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| Description | Anti-Phospho-AurB/C (Thr236/202) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AurB/C (Thr236/202). Anti-Phospho-AurB/C (Thr236/202) Polyclonal Antibody can be used in IHC. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | IHC: 1:50-100 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at 'Ser-10' and 'Ser-28'. Phosphorylates TACC1, another protein involved in cell division, at 'Ser-228'. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of threonine 236/202 (C-G-T(p)-L-D) derived from Human AurB/C |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 35 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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