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4-PQBH

Catalog No. T61428 CAS 2243355-51-1

4-PQBH is a potent Nur77-binding agent with antitumour activity.4-PQBH inhibits xenograft tumours through Nur77-mediated endoplasmic stress and autophagy by broadly inducing cysteoaspartase-independent cytoplasmic vacuolisation and parapetaloid ptosis.4-PQBH is used in the study of hepatocellular carcinoma.4-PQBH is a potent Nur77-binding agent with antitumour activity.

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4-PQBH, CAS 2243355-51-1

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1 mg	In stock	$ 69.00

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Purity: 99.08%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	367.4
Formula	C22H17N5O
CAS No.	2243355-51-1

Storage

keep away from direct sunlight,keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10 mg/mL (27.22 mM), Sonication is recommended.

References and Literature

1. Baicun Li, et al. Discovery of a Nur77-mediated cytoplasmic vacuolation and paraptosis inducer (4-PQBH) for the treatment of hepatocellular carcinoma. Bioorg Chem. 2022 Apr;121:105651.

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Keywords

4-PQBH 2243355-51-1 Others inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.