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Anti-CNDP1 Antibody (4Z744) (Synonyms: Cn1, carnosine dipeptidase 1 (metallopeptidase M20 family), AI746433)
Catalog No. TMAY-00226 Copy Product Info
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Anti-CNDP1 Antibody (4Z744) is a Mouse antibody targeting CNDP1. Anti-CNDP1 Antibody (4Z744) can be used in ELISA.
Anti-CNDP1 Antibody (4Z744)
Copy Product Info🥰Excellent
Catalog No. TMAY-00226
Synonyms Cn1, carnosine dipeptidase 1 (metallopeptidase M20 family), AI746433
Anti-CNDP1 Antibody (4Z744) is a Mouse antibody targeting CNDP1. Anti-CNDP1 Antibody (4Z744) can be used in ELISA.
Anti-CNDP1 Antibody
(4Z744)
(4Z744)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $198 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
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| Description | Anti-CNDP1 Antibody (4Z744) is a Mouse antibody targeting CNDP1. Anti-CNDP1 Antibody (4Z744) can be used in ELISA. |
| Synonyms | Cn1, carnosine dipeptidase 1 (metallopeptidase M20 family), AI746433 |
| Ig Type | Mouse IgG1 |
| Clone | 4Z744 |
| Reactivity | Human |
| Specificity | Human CNDP1 |
| Application | |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Carnosine Dipeptidase 1 (rhCNDP1; TMPY-00719; Ser27-His507; NP_116038.4). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CNDP1, also known as carnosine dipeptidase 1, glutamate carboxypeptidase-like protein 2 (CPGL-2) or carnosinase 1 (CN1), is a member of the M20 metalloprotease family. The CNDP1 gene contains trinucleotide (CTG) repeat length polymorphism in the coding region, which has been demonstrated to be associated with susceptibility to developing diabetic nephropathy, for carnosine protection against the adverse effects of high glucose levels on renal cells. In humans, CNDP1 is secreted from the liver into the serum. In other mammals, including rodents, CNDP1 is expressed exclusively within the kidney and lacks a signal peptide. CNDP1 protein is a secreted homodimeric dipeptidase that specifically hydrolyzes L-carnosine (β-alanyl-L-histidine), and is identified as human carnosinase expressed in the brain. CNDP1 has been associated with diabetic nephropathy in Europeans and European Americans, but not African-Americans. It was identified and confirmed as a risk factor, were cross-sectional and mostly in patients with type 2 diabetes. The polymorphisms of CNDP1 can be excluded as a risk factor for nephropathy in type 1 diabetes. In addition, CNDP1 is also suggested to be implicated in the actions of neuroprotection and neurotransmiting. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human CNDP1 Protein (TMPY-00719) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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