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Anti-M-CSF/CSF1 Polyclonal Antibody (Synonyms: MGC31930, M-CSF, MCSF, Lanimostim, CSF-1, CSF1)
Catalog No. TMAB-01120 Copy Product Info
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Anti-M-CSF/CSF1 Polyclonal Antibody is a Rabbit antibody targeting M-CSF/CSF1. Anti-M-CSF/CSF1 Polyclonal Antibody can be used in WB.
Anti-M-CSF/CSF1 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-01120
Synonyms MGC31930, M-CSF, MCSF, Lanimostim, CSF-1, CSF1
Anti-M-CSF/CSF1 Polyclonal Antibody is a Rabbit antibody targeting M-CSF/CSF1. Anti-M-CSF/CSF1 Polyclonal Antibody can be used in WB.
Anti-M-CSF/CSF1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-M-CSF/CSF1 Polyclonal Antibody is a Rabbit antibody targeting M-CSF/CSF1. Anti-M-CSF/CSF1 Polyclonal Antibody can be used in WB. |
| Synonyms | MGC31930, M-CSF, MCSF, Lanimostim, CSF-1, CSF1 |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog,Pig,Cow,Rabbit) |
| Verified Activity | Sample: Lung (Mouse) Lysate at 40 μg Primary: Anti-MCSF (TMAB-01120) at 1/300 dilution Secondary: HRP conjugated Goat-Anti-rabbit IgG (secondary antibody) at 1/5000 dilution Predicted band size: 57 kDa Observed band size: 57 kDa  |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass membrane protein. Processed macrophage colony-stimulating factor 1: Secreted, extracellular space. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Four distinct colony-stimulating factors (CSFs) that promote survival, proliferation and differentiation of bone marrow precursor cells have been well characterized: granulocyte macrophage CSF (GMCSF), granulocyte CSF (GCSF), macrophage CSF (MCSF), and Interleukin-3 (IL-3, Multi CSF). Both GMCSF and IL-3 are multipotential growth factors, stimulating proliferation of progenitor cells from more than one hematopoietic lineage. In contrast, GCSF and MCSF are lineage restricted hematopoietic growth factors, stimulating final mitotic divisions and the terminal cellular maturation of the partially differentiated hematopoietic progenitors. Macrophage CSF, also known as CSF1, is produced by monocytes, fibroblasts and endothelial cells. It stimulates the formation of macrophage colonies, enhances antibody-dependent, cell-mediated cytotoxicity by monocytes and macrophages, and inhibits bone resorption by osetoclasts. Natural human MCSF is a dimeric glycoprotein of 70-90 kD molecular weight, existing in multiple glycosylation forms. It binds to a 165 kD glycoprotein of the receptor tyrosine kinase subclass III, a family that includes the receptors for platelet derived growth factor (PDGF) and stem cell factor (SCF). |
| Immunogen | KLH conjugated synthetic peptide: human MCSF/M-CSF |
| Antigen Species | Human |
| Gene Name | CSF1 |
| Gene ID | |
| Protein Name | Macrophage colony-stimulating factor 1 |
| Uniprot ID | |
| Biology Area | Inflammatory mediators,CSFs,Cytokines and cytokine receptors ELISA kits |
| Function | Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance. |
| Molecular Weight | Theoretical: 57 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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