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Anti-M-CSF/CSF1 Polyclonal Antibody
😃Good
Catalog No. TMAB-01120
Anti-M-CSF/CSF1 Polyclonal Antibody is a Rabbit antibody targeting M-CSF/CSF1. Anti-M-CSF/CSF1 Polyclonal Antibody can be used in WB.
Anti-M-CSF/CSF1 Polyclonal Antibody
Anti-M-CSF/CSF1 Polyclonal Antibody
😃Good
Catalog No. TMAB-01120
Anti-M-CSF/CSF1 Polyclonal Antibody is a Rabbit antibody targeting M-CSF/CSF1. Anti-M-CSF/CSF1 Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $221 | 7-10 days | |
| 100 μL | $372 | 7-10 days | |
| 200 μL | $528 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-M-CSF/CSF1 Polyclonal Antibody is a Rabbit antibody targeting M-CSF/CSF1. Anti-M-CSF/CSF1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog,Pig,Cow,Rabbit) |
| Verified Activity | Sample: Lung (Mouse) Lysate at 40 μg Primary: Anti-MCSF (TMAB-01120) at 1/300 dilution Secondary: HRP conjugated Goat-Anti-rabbit IgG (secondary antibody) at 1/5000 dilution Predicted band size: 57 kDa Observed band size: 57 kDa |
| Application | WB |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass membrane protein. Processed macrophage colony-stimulating factor 1: Secreted, extracellular space. |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | Four distinct colony-stimulating factors (CSFs) that promote survival, proliferation and differentiation of bone marrow precursor cells have been well characterized: granulocyte macrophage CSF (GMCSF), granulocyte CSF (GCSF), macrophage CSF (MCSF), and Interleukin-3 (IL-3, Multi CSF). Both GMCSF and IL-3 are multipotential growth factors, stimulating proliferation of progenitor cells from more than one hematopoietic lineage. In contrast, GCSF and MCSF are lineage restricted hematopoietic growth factors, stimulating final mitotic divisions and the terminal cellular maturation of the partially differentiated hematopoietic progenitors. Macrophage CSF, also known as CSF1, is produced by monocytes, fibroblasts and endothelial cells. It stimulates the formation of macrophage colonies, enhances antibody-dependent, cell-mediated cytotoxicity by monocytes and macrophages, and inhibits bone resorption by osetoclasts. Natural human MCSF is a dimeric glycoprotein of 70-90 kD molecular weight, existing in multiple glycosylation forms. It binds to a 165 kD glycoprotein of the receptor tyrosine kinase subclass III, a family that includes the receptors for platelet derived growth factor (PDGF) and stem cell factor (SCF). |
| Immunogen | KLH conjugated synthetic peptide: human MCSF/M-CSF |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Inflammatory mediators,CSFs,Cytokines and cytokine receptors ELISA kits |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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