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Anti-Phospho-CDC25C (Ser198) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CDC25C (Ser198). Anti-Phospho-CDC25C (Ser198) Polyclonal Antibody can be used in IHC.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $217 | 7-10 days | 7-10 days | |
| 100 μL | $316 | 7-10 days | 7-10 days |
| Description | Anti-Phospho-CDC25C (Ser198) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CDC25C (Ser198). Anti-Phospho-CDC25C (Ser198) Polyclonal Antibody can be used in IHC. |
| Synonyms | p-CDC25C (Ser198), p-CDC25C (S198), CDC25C (p-Ser198), CDC25C (p-S198) |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using CDC25C (Phospho-Ser198) antibody TMAC-00764 (left) or the same antibody preincubated with blocking peptide (right). ![]() |
| Application | |
| Recommended Dose | IHC: 1:50-100 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of Serine 198(E-F-S(p)-L-K) derived from Human CDC25C |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 53 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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