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Anti-USP11 Antibody (1W222)
😃Good
Catalog No. TMAC-04202
Alias USP 11, UHX1, UBP11_HUMAN, Ubiquitin-specific-processing protease 11, Ubiquitin thiolesterase 11, Ubiquitin specific protease 11, ubiquitin specific peptidase 11, Ubiquitin carboxyl-terminal hydrolase X linked, Ubiquitin carboxyl-terminal hydrolase 11, Deubiquitinating enzyme 11
Anti-USP11 Antibody (1W222) is a Rabbit antibody targeting USP11. Anti-USP11 Antibody (1W222) can be used in WB,ICC/IF,IP,FCM.
Anti-USP11 Antibody (1W222)
Anti-USP11 Antibody (1W222)
😃Good
Catalog No. TMAC-04202Alias USP 11, UHX1, UBP11_HUMAN, Ubiquitin-specific-processing protease 11, Ubiquitin thiolesterase 11, Ubiquitin specific protease 11, ubiquitin specific peptidase 11, Ubiquitin carboxyl-terminal hydrolase X linked, Ubiquitin carboxyl-terminal hydrolase 11, Deubiquitinating enzyme 11
Anti-USP11 Antibody (1W222) is a Rabbit antibody targeting USP11. Anti-USP11 Antibody (1W222) can be used in WB,ICC/IF,IP,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-USP11 Antibody (1W222) is a Rabbit antibody targeting USP11. Anti-USP11 Antibody (1W222) can be used in WB,ICC/IF,IP,FCM. |
| Synonyms | USP 11, UHX1, UBP11_HUMAN, Ubiquitin-specific-processing protease 11, Ubiquitin thiolesterase 11, Ubiquitin specific protease 11, ubiquitin specific peptidase 11, Ubiquitin carboxyl-terminal hydrolase X linked, Ubiquitin carboxyl-terminal hydrolase 11, Deubiquitinating enzyme 11 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of USP11 on 293T cell using anti-USP11 antibody at 1/1,000 dilution. 2. ICC staining USP11 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining USP11 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining USP11 in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. Flow cytometric analysis of Jurkat cells with USP11 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). |
| Application | |
| Recommended Dose | WB: 1:500-1000; ICC/IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP11 (ubiquitin specific peptidase 11), also known as UHX1, is a 920 amino acid deubiquitinating enzyme that participates in the Ub pathway. Localized to the nucleus, USP11 associates with both Ran BP-M (Ran binding protein M) and with the tumor suppressor BRCA2. Through these associations, USP11 functions to either inhibit ubiquitination of these proteins or to remove ubiquitin residues that have already been attached to these proteins. USP11 is implicated in several X-linked retinal diseases and, due to its ability to deubiquitinate BRCA2, may play a role in tumor suppression. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 110 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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