PDGFA Protein, Human, Recombinant (His)

Name: PDGFA Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-05056
Rating: 4.5 (1 reviews)

(Synonyms: platelet-derived growth factor α polypeptide, platelet-derived growth factor alpha polypeptide, PDGF-A, PDGF1) Copy Product Info

Synonyms: platelet-derived growth factor α polypeptide, platelet-derived growth factor alpha polypeptide, PDGF-A, PDGF1

Catalog No. TMPY-05056 Copy Product Info

Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site. PDGFA Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 16.3 kDa and the accession number is AAA60045.1.

Pack Size	Price	USA Stock	Global Stock
5 µg	$87	7-10 days	7-10 days
10 µg	$142	7-10 days	7-10 days
20 µg	$233	7-10 days	7-10 days
50 µg	$462	7-10 days	7-10 days
100 µg	$746	7-10 days	7-10 days
200 µg	$1,200	7-10 days	7-10 days
500 µg	$2,250	7-10 days	7-10 days
1 mg	$4,230	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Western blot analysis of extracts from serum-starved NIH-3T3, untreated (-); treated with PDGFA (Cat#TMPY-05056) (5 μg/mL, 5 min; +), using Phospho-AKT (Ser473) rabbit monoclonal Antibody at 1:2000 dilution (upper) or anti-Akt antibody (lower) (Routinely tested).
Description	Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site. PDGFA Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 16.3 kDa and the accession number is AAA60045.1.
Species	Human
Expression System	P. pastoris (Yeast)
Tag	N-His
Accession Number	AAA60045.1
Construction	A DNA sequence encoding the human PDGFA (AAA60045.1) (Ser87-Thr211) was expressed with a polyhistidine tag at the N-terminus. Predicted N terminal: His
Protein Purity	> 95 % as determined by SDS-PAGE.
Endotoxin	Please contact us for more information.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 30% CAN, 0.1% TFA. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	platelet-derived growth factor α polypeptide, platelet-derived growth factor alpha polypeptide, PDGF-A, PDGF1
Research Background	Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis. The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site.

Chemical Properties

Molecular Weight

16.3 kDa (predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.