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1-vinylpyrene (1-Ethenylpyrene) has antitumor activity and strongly inhibits the formation of skin tumors triggered by DMBA or B[]P in a dose-dependent manner and can be used to prevent tumor formation.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 mg | $40 | In Stock | In Stock | |
| 10 mg | $56 | In Stock | In Stock | |
| 25 mg | $98 | In Stock | In Stock | |
| 50 mg | $152 | In Stock | In Stock | |
| 100 mg | $228 | In Stock | In Stock |
| Description | 1-vinylpyrene (1-Ethenylpyrene) has antitumor activity and strongly inhibits the formation of skin tumors triggered by DMBA or B[]P in a dose-dependent manner and can be used to prevent tumor formation. |
| In vitro | 1-vinylpyrene (VP) (single dose; topical application; Preconditioning 5 minutes before an initiating dose) inhibited tumor initiation by 10 nmol of DMBA by approximately 30%; application of 4.4 nmol of VP inhibited tumor initiation by 200 nmol of B[a]P approximately 56%. A.[2] |
| Synonyms | 1-Ethenylpyrene |
| Molecular Weight | 228.29 |
| Formula | C18H12 |
| Cas No. | 17088-21-0 |
| Smiles | C(=C)C1=C2C3=C4C(C=C2)=CC=CC4=CC=C3C=C1 |
| Relative Density. | 1.1209 g/cm3 (Estimated) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||
| Solubility Information | DMSO: 0.57 mg/mL (2.5 mM), Sonication is recommended. | ||||||||||
Solution Preparation Table | |||||||||||
DMSO
| |||||||||||
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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