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AIMP2-DX2-IN-1

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Catalog No. T61326Cas No. 848256-17-7

AIMP2-DX2-IN-1 is a potent AIMP2-DX2 inhibitor with potential antitumor activity for the study of lymphoma.

AIMP2-DX2-IN-1

AIMP2-DX2-IN-1

😃Good
Purity: 99.53%
Catalog No. T61326Cas No. 848256-17-7
AIMP2-DX2-IN-1 is a potent AIMP2-DX2 inhibitor with potential antitumor activity for the study of lymphoma.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$33In StockIn Stock
5 mg$77In StockIn Stock
10 mg$128In StockIn Stock
25 mg$215In StockIn Stock
50 mg$320In StockIn Stock
100 mg$455-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.53%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
AIMP2-DX2-IN-1 is a potent AIMP2-DX2 inhibitor with potential antitumor activity for the study of lymphoma.
Targets&IC50
AIMP2-DX2:0.1063 μM
In vitro
At a duration of 96 hours and concentrations ranging from 0 to 1 μM, AIMP2-DX2-IN-1 (Compound 35) demonstrates inhibitory activity against A549 and H460 cells while exhibiting no toxicity for normal cells [1].AIMP2-DX2-IN-1 exhibits very poor metabolic stability and good plasma stability in both human and mouse. Improvement in CYP inhibition is necessary [1].
Chemical Properties
Molecular Weight359.42
FormulaC23H21NO3
Cas No.848256-17-7
SmilesC(NC(CC1=CC=C(C=C1)C2=CC=CC=C2)=O)C3OC=4C(OC3)=CC=CC4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

AIMP2-DX2
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