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Palmitoylcarnitine (Alias: Palmitoyl DL-carnitine)

Catalog No. T12356 Copy Product Info
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Palmitoylcarnitine (Palmitoyl DL-carnitine) is a mitochondrial fatty acid oxidation intermediate that acts as a surfactant.

Palmitoylcarnitine

Copy Product Info
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Catalog No. T12356
Alias Palmitoyl DL-carnitine

Palmitoylcarnitine (Palmitoyl DL-carnitine) is a mitochondrial fatty acid oxidation intermediate that acts as a surfactant.

Palmitoylcarnitine
Cas No. 1935-18-8
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$158In StockIn Stock
5 mg$398In StockIn Stock
10 mg$572In StockIn Stock
25 mg$893In StockIn Stock
50 mg$1,230-In Stock
100 mg$1,630-In Stock
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:>99.99%
Appearance:Solid
Color:White
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Product Introduction

Palmitoylcarnitine AI Summary
Palmitoylcarnitine shows a broad range of bioactivities, including inhibition of protein kinase C (PKC) purified from rat brain with an IC50 value of 15800.0 nM. It plays a role in mitochondrial processes, such as division and activation of mitochondrial fusion, and interacts with the human D1 dopamine receptor. The compound inhibits mammalian selenoprotein thioredoxin reductase 1 (TrxR1), histone lysine methyltransferase G9a, and other enzymes and pathways associated with chronic active B-cell receptor signaling, ATXN expression, human flap endonuclease 1 (FEN1), Lassa Virus entry, USP1/UAF1, human tyrosyl-DNA phosphodiesterase 1 (TDP1), and alpha-synuclein. Additionally, it mitigates cellular toxicity induced by Amyloid beta peptide. In terms of carnitine transport, Palmitoylcarnitine inhibits Palmitoyl-carnitine by 28.0% at 5 µM in Octn2-HEK cells and shows an activity of 54.0 µM in Octn3-HEK cells..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Palmitoylcarnitine (Palmitoyl DL-carnitine) is a mitochondrial fatty acid oxidation intermediate that acts as a surfactant.
SynonymsPalmitoyl DL-carnitine
Chemical Properties
Molecular Weight399.61
FormulaC23H45NO4
Cas No.1935-18-8
SmilesO=C([O-])CC(OC(=O)CCCCCCCCCCCCCCC)C[N+](C)(C)C
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 4.03 mg/mL (10.08 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5024 mL12.5122 mL25.0244 mL125.1220 mL
5 mM0.5005 mL2.5024 mL5.0049 mL25.0244 mL
10 mM0.2502 mL1.2512 mL2.5024 mL12.5122 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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