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Anti-CD48 Antibody-PE (1M803) is a PE-conjugated Rabbit antibody targeting CD48. Anti-CD48 Antibody-PE (1M803) can be used in FCM.
Description | Anti-CD48 Antibody-PE (1M803) is a PE-conjugated Rabbit antibody targeting CD48. Anti-CD48 Antibody-PE (1M803) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 1M803 |
Reactivity | Mouse |
Verified Activity | Flow cytometric analysis of CD48 expression on spleen lymphocytes. BALB/c splenocytes were treated with Mouse BD Fc Block™ purified anti-CD16/CD32 mAb 2.4G2 and stained with PE-conjugated anti-Mouse CD48. The histogram were derived from the gated events based on light scattering characteristics of lymphocytes. |
Application | FCM |
Recommended Dose | 10 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD48 / SLAMF2 (rM CD48 / SLAMF2; TMPY-01372; NP_031675.1; Met 1-Arg 216) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
Research Background | Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
Conjucates | PE |
Others Formats | Unconjugated/APC/PerCP/FITC/HRP |
Antibody Types Available | 6 |
Immunogen | Recombinant Mouse CD48 / SLAMF2 protein (TMPY-01372) |
Antigen Species | Mouse |
Biology Area | Cancer Drug Targets |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
Transport | Shipping with blue ice. |
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