CD30L Protein, Human, Recombinant

Name: CD30L Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPY-04581
Rating: 4.5 (1 reviews)

(Synonyms: tumor necrosis factor (ligand) superfamily, member 8, CD30LG, CD30L, CD153) Copy Product Info

Synonyms: tumor necrosis factor (ligand) superfamily, member 8, CD30LG, CD30L, CD153

Catalog No. TMPY-04581 Copy Product Info

CD30L Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19.6 kDa and the accession number is P32971.

Pack Size	Price	USA Stock	Global Stock
5 µg	$55	7-10 days	7-10 days
10 µg	$85	7-10 days	7-10 days
20 µg	$138	7-10 days	7-10 days
50 µg	$276	7-10 days	7-10 days
100 µg	$460	7-10 days	7-10 days
200 µg	$896	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	CD30L Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19.6 kDa and the accession number is P32971.
Species	Human
Expression System	HEK293 Cells
Tag	Tag Free
Accession Number	P32971
Construction	A DNA sequence encoding the human CD30L (NP_001235.1) (Gln63-Asp234) was expressed with two additional amino acids (Gly & Pro ) at the N-terminus. Predicted N terminal: Gln 63
Protein Purity	> 90 % as determined by SDS-PAGE.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	tumor necrosis factor (ligand) superfamily, member 8, CD30LG, CD30L, CD153
Research Background	CD30 ligand (CD30L), also known as CD153 and TNFSF8, is a membrane-associated glycoprotein belonging to the TNF superfamily and TNFR superfamily, and is a specific ligand for CD30/TNFRSF8 originally described as a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. CD30L is a type-II membrane glycoprotein expressed on activated T cells, stimulated monocyte-macrophages, granulocytes, eosinophils, and some Burkitt-like lymphoma cell lines. CD30L is capable of transducing signals through CD30 on different CD30+ lymphoma cell lines, and mediates pleiotropic biologic effects including cell proliferation, activation, differentiation, as well as cell death by apoptosis. CD30-CD30 ligand interaction has been suggested to have a pathophysiologic role in malignant lymphomas, particularly Hodgkin disease, large cell anaplastic lymphomas and Burkitt lymphomas, and is also involved in activation and functioning of the T cell-dependent immune response. Thus, CD153 and its receptor CD30 are regarded as therapeutic targets in hematologic malignancies, autoimmune and inflammatory diseases.

Chemical Properties

Molecular Weight

19.6 kDa (predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.