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Tolnapersine

Name: Tolnapersine
Brand: TargetMol
SKU: T68023
Rating: 4.5 (1 reviews)

😃Good

Catalog No. T68023Cas No. 70312-00-4

Tolnapersine is a mixed dopamine agonist and alpha-adrenoceptor antagonist.

Tolnapersine

😃Good

Catalog No. T68023Cas No. 70312-00-4

Tolnapersine is a mixed dopamine agonist and alpha-adrenoceptor antagonist.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$128	1-2 weeks	1-2 weeks
5 mg	$320	1-2 weeks	1-2 weeks
10 mg	$470	1-2 weeks	1-2 weeks
25 mg	$919	1-2 weeks	1-2 weeks
50 mg	$1,250	1-2 weeks	1-2 weeks
100 mg	$1,940	1-2 weeks	1-2 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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COA

Product Introduction

Bioactivity

Description	Tolnapersine is a mixed dopamine agonist and alpha-adrenoceptor antagonist.
In vivo	Tolnapersine (BK 34/530) (50 and 100 mg; orally) a compound with mixed dopamine agonist and α-adrenoceptor antagonist activity, impaired gastric adaptive relaxation as measured by the volume 5 min after the 50 mg dose and at the higher dose delayed gastric emptying as compared to placebo and in the case of BK 34/530, the 100 mg dose caused significant tachycardia.[1]

Chemical Properties

Molecular Weight	322.44
Formula	C₂₁H₂₆N₂O
Cas No.	70312-00-4
Smiles	OC1=CC=C2C(=C1)CCC(N3CCN(C=4C=CC=CC4C)CC3)C2
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc