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Anti-WHSC2 Antibody (5N717) (Synonyms: Wolf-Hirschhorn syndrome candidate 2 protein, Wolf Hirschhorn syndrome c...)

Catalog No. TMAC-04282 Copy Product Info
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Anti-WHSC2 Antibody (5N717) is a Mouse antibody targeting WHSC2. Anti-WHSC2 Antibody (5N717) can be used in FCM,ICC,IHC,WB.

Anti-WHSC2 Antibody (5N717)

Copy Product Info
🥰Excellent
Catalog No. TMAC-04282
Synonyms Wolf-Hirschhorn syndrome candidate 2 protein, Wolf Hirschhorn syndrome candidate 2 protein, Wolf Hirschhorn syndrome candidate 2, WHSC 2, P/OKcl15, P/OKcl.15, NELFA_HUMAN, NELF-A, NELFA, NELF A, Negative elongation factor polypeptide A, Negative elongation factor A, FLJ25112, FLJ10442

Anti-WHSC2 Antibody (5N717) is a Mouse antibody targeting WHSC2. Anti-WHSC2 Antibody (5N717) can be used in FCM,ICC,IHC,WB.

Anti-WHSC2 Antibody
(5N717)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-WHSC2 Antibody (5N717) is a Mouse antibody targeting WHSC2. Anti-WHSC2 Antibody (5N717) can be used in FCM,ICC,IHC,WB.
SynonymsWolf-Hirschhorn syndrome candidate 2 protein, Wolf Hirschhorn syndrome candidate 2 protein, Wolf Hirschhorn syndrome candidate 2, WHSC 2, P/OKcl15, P/OKcl.15, NELFA_HUMAN, NELF-A, NELFA, NELF A, Negative elongation factor polypeptide A, Negative elongation factor A, FLJ25112, FLJ10442
Clone
5N717
Reactivity
Human,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:100-200; ICC: 1:50-200; FCM: 1:100-200
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundNELF-A, for negative elongation factor A, is a protein factor required for DRB-sensitive transcription. NELF-A is one of the five components of the multisubunit NELF complex that cooperates with DSIF to repress RNA polymerase II elongation. Control of transcription elongation requires a complex interplay between positive transcription elongation factor b (P-TEFb) and negative transcription elongation factors, DSIF and NELF. DSIF and NELF act as negative transcription elongation factors by increasing the time the polymerase spends at pause sites. DSIF/NELF inhibition of transcription is prevented by P-TEFb in cooperation with FACT. NELF-A is also known as WHSC2 (Wolf-Hirschhorn syndrome candidate 2). Wolf-Hirschhorn syndrome is a multiple malformation syndrome characterized by mental and developmental defects resulting from a hemizygous deletion of the distal short arm of chromosome 4 (4p16.3). The human NELF-A gene maps to chromosome 4p16.3 and encodes a 528 amino acid protein that is expressed in endothelial cells.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 57 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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