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Anti-WHSC2 Antibody (5N717)
😃Good
Catalog No. TMAC-04282
Alias Wolf-Hirschhorn syndrome candidate 2 protein, Wolf Hirschhorn syndrome candidate 2 protein, Wolf Hirschhorn syndrome candidate 2, WHSC 2, P/OKcl15, P/OKcl.15, NELFA_HUMAN, NELF-A, NELFA, NELF A, Negative elongation factor polypeptide A, Negative elongation factor A, FLJ25112, FLJ10442
Anti-WHSC2 Antibody (5N717) is a Mouse antibody targeting WHSC2. Anti-WHSC2 Antibody (5N717) can be used in FCM,ICC,IHC,WB.
Anti-WHSC2 Antibody (5N717)
Anti-WHSC2 Antibody (5N717)
😃Good
Catalog No. TMAC-04282Alias Wolf-Hirschhorn syndrome candidate 2 protein, Wolf Hirschhorn syndrome candidate 2 protein, Wolf Hirschhorn syndrome candidate 2, WHSC 2, P/OKcl15, P/OKcl.15, NELFA_HUMAN, NELF-A, NELFA, NELF A, Negative elongation factor polypeptide A, Negative elongation factor A, FLJ25112, FLJ10442
Anti-WHSC2 Antibody (5N717) is a Mouse antibody targeting WHSC2. Anti-WHSC2 Antibody (5N717) can be used in FCM,ICC,IHC,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $427 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-WHSC2 Antibody (5N717) is a Mouse antibody targeting WHSC2. Anti-WHSC2 Antibody (5N717) can be used in FCM,ICC,IHC,WB. |
| Synonyms | Wolf-Hirschhorn syndrome candidate 2 protein, Wolf Hirschhorn syndrome candidate 2 protein, Wolf Hirschhorn syndrome candidate 2, WHSC 2, P/OKcl15, P/OKcl.15, NELFA_HUMAN, NELF-A, NELFA, NELF A, Negative elongation factor polypeptide A, Negative elongation factor A, FLJ25112, FLJ10442 |
| Clone | 5N717 |
| Reactivity | Human,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:100-200; ICC: 1:50-200; FCM: 1:100-200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | NELF-A, for negative elongation factor A, is a protein factor required for DRB-sensitive transcription. NELF-A is one of the five components of the multisubunit NELF complex that cooperates with DSIF to repress RNA polymerase II elongation. Control of transcription elongation requires a complex interplay between positive transcription elongation factor b (P-TEFb) and negative transcription elongation factors, DSIF and NELF. DSIF and NELF act as negative transcription elongation factors by increasing the time the polymerase spends at pause sites. DSIF/NELF inhibition of transcription is prevented by P-TEFb in cooperation with FACT. NELF-A is also known as WHSC2 (Wolf-Hirschhorn syndrome candidate 2). Wolf-Hirschhorn syndrome is a multiple malformation syndrome characterized by mental and developmental defects resulting from a hemizygous deletion of the distal short arm of chromosome 4 (4p16.3). The human NELF-A gene maps to chromosome 4p16.3 and encodes a 528 amino acid protein that is expressed in endothelial cells. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 57 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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