Ponasterone A

Name: Ponasterone A
Brand: TargetMol
SKU: T21205
Price: 99 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T21205Cas No. 13408-56-5

Alias AI3-44686

Ponasterone A is an ecdysteroid with high affinity for the ecdysteroid receptor. It enables rapid switching on and off of reporter genes and is a potent regulator of gene expression in cells and transgenic animals.

Ponasterone A

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Purity: 95.74%

Catalog No. T21205Alias AI3-44686Cas No. 13408-56-5

Pack Size	Price	Availability	Quantity
1 mg	$99	In Stock

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Purity:95.74%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Ponasterone A is an ecdysteroid with high affinity for the ecdysteroid receptor. It enables rapid switching on and off of reporter genes and is a potent regulator of gene expression in cells and transgenic animals.
In vitro	Ponasterone A showed significant gene-induced activity in CV-1 cells[2].
In vivo	Ponasterone A induces strong gene expression in Transactivator and reporter mice[2].
Synonyms	AI3-44686

Chemical Properties

Molecular Weight	464.63
Formula	C₂₇H₄₄O₆
Cas No.	13408-56-5
Smiles	CC(C)CC[C@@H](O)[C@](C)(O)[C@H]1CCC2(O)C3=CC(=O)[C@@H]4C[C@@H](O)[C@@H](O)C[C@]4(C)[C@H]3CC[C@]12C
Relative Density.	1.22 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage	store at low temperature \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	DMSO: Soluble

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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