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Pyridostigmine bromide

Name: Pyridostigmine bromide
Brand: TargetMol
SKU: T0780
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0780Cas No. 101-26-8

Alias Mestinon

Pyridostigmine bromide (Mestinon) is a cholinesterase inhibitor with a slightly longer duration of action than NEOSTIGMINE. It is used in the treatment of myasthenia gravis and to reverse the actions of muscle relaxants.

Pyridostigmine bromide

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Purity: 99.98%

Catalog No. T0780Alias MestinonCas No. 101-26-8

Pack Size	Price	Availability
200 mg	$30	In Stock
500 mg	$45	In Stock
1 g	$76	In Stock

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Batch Information

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Purity:99.98%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Pyridostigmine bromide (Mestinon) is a cholinesterase inhibitor with a slightly longer duration of action than NEOSTIGMINE. It is used in the treatment of myasthenia gravis and to reverse the actions of muscle relaxants.
Synonyms	Mestinon

Chemical Properties

Molecular Weight	261.12
Formula	C₉H₁₃BrN₂O₂
Cas No.	101-26-8
Smiles	[Br-].CN(C)C(=O)Oc1c[n+](C)ccc1
Relative Density.	0.9613 g/cm3 (20°C)

Storage & Solubility Information

Storage

keep away from moisture | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 48 mg/mL (183.82 mM), Sonication is recommended.

Ethanol: 49 mg/mL (187.65 mM), Sonication is recommended.

DMSO: 50 mg/mL (191.48 mM), Sonication is recommended.

Solution Preparation Table

H2O/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.8297 mL	19.1483 mL	38.2966 mL	191.4828 mL
5 mM	0.7659 mL	3.8297 mL	7.6593 mL	38.2966 mL
10 mM	0.3830 mL	1.9148 mL	3.8297 mL	19.1483 mL
20 mM	0.1915 mL	0.9574 mL	1.9148 mL	9.5741 mL
50 mM	0.0766 mL	0.3830 mL	0.7659 mL	3.8297 mL
100 mM	0.0383 mL	0.1915 mL	0.3830 mL	1.9148 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc