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Fmoc-PEG4-NHS ester

Name: Fmoc-PEG4-NHS ester
Brand: TargetMol
SKU: T15332
Rating: 4.5 (1 reviews)

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Catalog No. T15332Cas No. 1314378-14-7

Fmoc-PEG4-NHS ester is a PEG-based PROTAC linker that can be used to synthesise PROTAC molecules.

Fmoc-PEG4-NHS ester

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Catalog No. T15332Cas No. 1314378-14-7

Fmoc-PEG4-NHS ester is a PEG-based PROTAC linker that can be used to synthesise PROTAC molecules.

Pack Size	Price	Availability	Quantity
200 mg	$29	7-10 days

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Product Introduction

Bioactivity

Description

Fmoc-PEG4-NHS ester is a PEG-based PROTAC linker that can be used to synthesise PROTAC molecules.

Chemical Properties

Molecular Weight	584.61
Formula	C₃₀H₃₆N₂O₁₀
Cas No.	1314378-14-7
Smiles	O=C(OCC1C=2C=CC=CC2C=3C=CC=CC31)NCCOCCOCCOCCOCCC(=O)ON4C(=O)CCC4=O
Relative Density.	1.32 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (136.84 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7105 mL	8.5527 mL	17.1054 mL	85.5271 mL
5 mM	0.3421 mL	1.7105 mL	3.4211 mL	17.1054 mL
10 mM	0.1711 mL	0.8553 mL	1.7105 mL	8.5527 mL
20 mM	0.0855 mL	0.4276 mL	0.8553 mL	4.2764 mL
50 mM	0.0342 mL	0.1711 mL	0.3421 mL	1.7105 mL
100 mM	0.0171 mL	0.0855 mL	0.1711 mL	0.8553 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc