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RNAIII-inhibiting peptide TFA

Name: RNAIII-inhibiting peptide TFA
Brand: TargetMol
SKU: TP1412
Price: 78 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TP1412

Alias RNAIII-inhibiting peptide(TFA)

RNAIII-inhibiting peptide TFA (RNAIII-inhibiting peptide(TFA))(228544-21-6 free base) inhibits S. aureus, effective in the diseases such as cellulitis, keratitis, septic arthritis, osteomylitis and mastitis.

RNAIII-inhibiting peptide TFA

🥰Excellent

Purity: 98.68%

Catalog No. TP1412Alias RNAIII-inhibiting peptide(TFA)

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$78	In Stock	In Stock
5 mg	$251	In Stock	In Stock
10 mg	$327	In Stock	In Stock
25 mg	$423	In Stock	In Stock
50 mg	$550	In Stock	In Stock
100 mg	$713	In Stock	In Stock
200 mg	$966	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$331	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.68%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	RNAIII-inhibiting peptide TFA (RNAIII-inhibiting peptide(TFA))(228544-21-6 free base) inhibits S. aureus, effective in the diseases such as cellulitis, keratitis, septic arthritis, osteomylitis and mastitis.
In vitro	The RNAIII inhibiting peptide (RIP) is able to inhibit S. aureus pathogenesis by disrupting QS mechanism competing with RAP, thus inhibiting the phosphorylation of TRAP. This alteration leads to a reduced adhesion and to the inhibition of RNAIII synthesis, with the subsequent suppression of toxins synthesis.
Synonyms	RNAIII-inhibiting peptide(TFA)

Chemical Properties

Molecular Weight	1027.01
Formula	C₄₇H₅₇F₃N₁₀O₁₃
Smiles	C[C@H]([C@@H](C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CO)NC(=O)[C@H](CC5=CC=C(C=C5)O)N)O.C(=O)(C(F)(F)F)O
Relative Density.	no data available
Sequence	Tyr-Ser-Pro-Trp-Thr-Asn-Phe
Sequence Short	YSPWTNF

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 247.5 mg/mL (240.99 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	0.9737 mL	4.8685 mL	9.7370 mL	48.6850 mL
5 mM	0.1947 mL	0.9737 mL	1.9474 mL	9.7370 mL
10 mM	0.0974 mL	0.4869 mL	0.9737 mL	4.8685 mL
20 mM	0.0487 mL	0.2434 mL	0.4869 mL	2.4343 mL
50 mM	0.0195 mL	0.0974 mL	0.1947 mL	0.9737 mL
100 mM	0.0097 mL	0.0487 mL	0.0974 mL	0.4869 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc