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Anti-SOD1 Antibody-PE (8C907)
🥰Excellent
Catalog No. TMAY-02022P
Anti-SOD1 Antibody-PE (8C907) is a PE-conjugated Mouse antibody targeting SOD1. Anti-SOD1 Antibody-PE (8C907) can be used in FCM.
Anti-SOD1 Antibody-PE (8C907)
Anti-SOD1 Antibody-PE (8C907)
🥰Excellent
Catalog No. TMAY-02022P
Anti-SOD1 Antibody-PE (8C907) is a PE-conjugated Mouse antibody targeting SOD1. Anti-SOD1 Antibody-PE (8C907) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-SOD1 Antibody-PE (8C907) is a PE-conjugated Mouse antibody targeting SOD1. Anti-SOD1 Antibody-PE (8C907) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG2b |
| Clone | 8C907 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human SOD1 expression in HeLa cells. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SOD1 (rh SOD1; TMPY-01585; NP_000445.1; Ala2-Gln154) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | SOD1 belongs to the Cu-Zn superoxide dismutase family. It binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. SOD1 destroys radicals which are normally produced within the cells and which are toxic to biological systems. Defects in SOD1 are the cause of amyotrophic lateral sclerosis type 1 (ALS1). ALS1 is a familial form of amyotrophic lateral sclerosis, a neurodegenerative disorder affecting upper and lower motor neurons and resulting in fatal paralysis. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. The etiology of amyotrophic lateral sclerosis is likely to be multifactorial, involving both genetic and environmental factors. The disease is inherited in 5-10% of cases leading to familial forms. |
| Conjucates | PE |
| Others Formats | Unconjugated/FITC |
| Antibody Types Available | 3 |
| Immunogen | Recombinant Human SOD1 protein (TMPY-01585) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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