Shopping Cart
Remove All
Your shopping cart is currently empty
Perlapine (Synonyms: MP-11)
Catalog No. T33937 Copy Product Info
Purity: 99.82%
🥰Excellent
Perlapine is a potent DREADD (Designer Receptors Exclusively Activated by Designer Drugs) agonist that specifically targets mutant muscarinic receptors. It exhibits remarkable selectivity for the hM3Dq mutant receptor, with a binding affinity and potency more than 10,000-fold higher than that for the wild-type hM3 receptor. As a pivotal chemogenetic tool, Perlapine enables highly specific activation of DREADD-expressing neurons, facilitating precise modulation in neural circuit and behavioral research.
Perlapine
Copy Product Info🥰Excellent
Catalog No. T33937
Synonyms MP-11
Perlapine is a potent DREADD (Designer Receptors Exclusively Activated by Designer Drugs) agonist that specifically targets mutant muscarinic receptors. It exhibits remarkable selectivity for the hM3Dq mutant receptor, with a binding affinity and potency more than 10,000-fold higher than that for the wild-type hM3 receptor. As a pivotal chemogenetic tool, Perlapine enables highly specific activation of DREADD-expressing neurons, facilitating precise modulation in neural circuit and behavioral research.
Cas No. 1977-11-3
Customer service consultation
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $71 | - | In Stock | |
| 5 mg | $169 | - | In Stock | |
| 10 mg | $312 | - | In Stock | |
| 25 mg | $526 | - | In Stock | |
| 50 mg | $749 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Batch Information
Select Batch
Purity:99.82%
Appearance:Solid
Color:White
Contact us for more batch information
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Perlapine is a potent DREADD (Designer Receptors Exclusively Activated by Designer Drugs) agonist that specifically targets mutant muscarinic receptors. It exhibits remarkable selectivity for the hM3Dq mutant receptor, with a binding affinity and potency more than 10,000-fold higher than that for the wild-type hM3 receptor. As a pivotal chemogenetic tool, Perlapine enables highly specific activation of DREADD-expressing neurons, facilitating precise modulation in neural circuit and behavioral research. |
| In vitro | Perlapine specifically activates hM3Dq with >10,000-fold selectivity over wild-type hM3[1]. |
| In vivo | Perlapine alters dopamine turnover, stimulates prolactin, and exhibits sedative/hypnotic properties in rats[1][2]. |
| Synonyms | MP-11 |
| Molecular Weight | 291.39 |
| Formula | C19H21N3 |
| Cas No. | 1977-11-3 |
| Smiles | N=1C=2C=CC=CC2CC=3C=CC=CC3C1N4CCN(C)CC4 |
| Relative Density. | 1.0521 g/cm3 (Estimated) |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Perlapine | purchase Perlapine | Perlapine cost | order Perlapine | Perlapine chemical structure | Perlapine in vivo | Perlapine in vitro | Perlapine formula | Perlapine molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.