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Anti-Aquaporin-4/AQP4 Antibody (8R110)

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Catalog No. TMAH-00077 Copy Product Info
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Anti-Aquaporin-4/AQP4 Antibody (8R110) is an antibody targeting Aquaporin-4/AQP4. Anti-Aquaporin-4/AQP4 Antibody (8R110) can be used in ELISA,IHC.
Anti-Aquaporin-4/AQP4 Antibody
(8R110)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2077-10 days7-10 days
100 μL$3487-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Aquaporin-4/AQP4 Antibody (8R110) is an antibody targeting Aquaporin-4/AQP4. Anti-Aquaporin-4/AQP4 Antibody (8R110) can be used in ELISA,IHC.
Ig Type
Rabbit IgG
Clone
8R110
Reactivity
Human
Application
Recommended Dose
IHC:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationCell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Endosome membrane. Cell membrane, sarcolemma; Multi-pass membrane protein. Cell projection.
Tissue SpecificityDetected in skeletal muscle. Detected in stomach, along the glandular base region of the fundic gland (at protein level). Detected in brain, lung and skeletal muscle, and at much lower levels in heart and ovary.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundForms a water-specific channel. Plays an important role in brain water homeostasis and in glymphatic solute transport. Required for a normal rate of water exchange across the blood brain interface. Required for normal levels of cerebrospinal fluid influx into the brain cortex and parenchyma along paravascular spaces that surround penetrating arteries, and for normal drainage of interstitial fluid along paravenous drainage pathways. Thereby, it is required for normal clearance of solutes from the brain interstitial fluid, including soluble beta-amyloid peptides derived from APP. Plays a redundant role in urinary water homeostasis and urinary concentrating ability.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human AQP4
Antigen Species
Human
Gene Name
AQP4
Gene ID
Uniprot ID
Biology Area
Cancer, Metabolism, Signal transduction
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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