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HIF-1 alpha (556-574)

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Catalog No. TP1533Cas No. 1201633-99-9
Alias HIF-1 alpha 556-574

HIF-1 alpha (556-574) is a hypoxia-inducible factor-1 19-mer fragment. HIF-1 functions as a master regulator of oxygen homeostasis by initiating hypoxia-induced gene expression when the HIF-1 subunit is stabilized due to lack of oxygen. This fragment binds to the von Hippel-Lindau factor (VHL), an E3 ubiquitin ligase, with proline 564 being essential to the binding process.

HIF-1 alpha (556-574)
Other Forms of HIF-1 alpha (556-574):
HIF-1 alpha (556-574) TFA (1201633-99-9 free base)TP1546
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HIF-1 alpha (556-574)

😃Good
Catalog No. TP1533Alias HIF-1 alpha 556-574Cas No. 1201633-99-9
HIF-1 alpha (556-574) is a hypoxia-inducible factor-1 19-mer fragment. HIF-1 functions as a master regulator of oxygen homeostasis by initiating hypoxia-induced gene expression when the HIF-1 subunit is stabilized due to lack of oxygen. This fragment binds to the von Hippel-Lindau factor (VHL), an E3 ubiquitin ligase, with proline 564 being essential to the binding process.
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Bioactivity
Description
HIF-1 alpha (556-574) is a hypoxia-inducible factor-1 19-mer fragment. HIF-1 functions as a master regulator of oxygen homeostasis by initiating hypoxia-induced gene expression when the HIF-1 subunit is stabilized due to lack of oxygen. This fragment binds to the von Hippel-Lindau factor (VHL), an E3 ubiquitin ligase, with proline 564 being essential to the binding process.
SynonymsHIF-1 alpha 556-574
Chemical Properties
Molecular Weight2254.6
FormulaC101H150D2N20O34S2
Cas No.1201633-99-9
SmilesC([C@@H](NC([C@@H](NC(=O)[C@H]1N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)CC(C)C)=O)CC(O)=O)=O)CC(C)C)=O)CCC(O)=O)=O)CCSC)=O)CC(C)C)=O)C)=O)C[C@@H]([C@@H]1[2H])[2H])CC2=CC=C(O)C=C2)=O)[C@H](CC)C)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)CCC(N)=O)=O)=O)CC(O)=O)=O)CC(O)=O)=O)CC(O)=O)=O)CCSC)=O)CCC3
Relative Density.no data available
Sequence ShortDLDLEMLAPYIPMDDDFQL
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: Soluble

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Keywords

HIF-1 α 556-574HIF1 alpha (556574)HIF-1 alphaHIF-1 a 556-574HIF 1 alpha (556 574)
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