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Anti-TIE2 Antibody-PE (1E654)
🥰Excellent
Catalog No. TMAY-01087P
Anti-TIE2 Antibody-PE (1E654) is a PE-conjugated Mouse antibody targeting TIE2. Anti-TIE2 Antibody-PE (1E654) can be used in FCM.
Anti-TIE2 Antibody-PE (1E654)
Anti-TIE2 Antibody-PE (1E654)
🥰Excellent
Catalog No. TMAY-01087P
Anti-TIE2 Antibody-PE (1E654) is a PE-conjugated Mouse antibody targeting TIE2. Anti-TIE2 Antibody-PE (1E654) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-TIE2 Antibody-PE (1E654) is a PE-conjugated Mouse antibody targeting TIE2. Anti-TIE2 Antibody-PE (1E654) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 1E654 |
| Reactivity | Human |
| Verified Activity | Profile of anti-Human TIE2 (CD202b) reactivity on HUVEC cells analyzed by flow cytometry. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Tie2 / CD202b / TEK (rh Tie2 / CD202b / TEK; TMPY-01064; AAA61139.1; Met1-Lys745) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | TEK, or TIE-2, is an endothelial cell-specific receptor tyrosine kinase (RTK) that is known as a functioning molecule of vascular endothelial cells. TEK comprises a subfamily of RTK with TIE, and these two receptors play critical roles in vascular maturation, maintenance of integrity and remodeling. Targeted mutagenesis of both Tek and its agonistic ligand, Angiopoietin-1, result in embryonic lethality, demonstrating that the signal transduction pathways mediated by this receptor are crucial for normal embryonic development. TEK signaling is indispensable for the development of the embryonic vasculature and suggests that TEK signaling may also be required for the development of the tumor vasculature. |
| Conjucates | PE |
| Others Formats | Unconjugated/APC/FITC |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human Tie2 / CD202b / TEK protein (TMPY-01064) |
| Antigen Species | Human |
| Biology Area | Receptor Tyrosine Kinases (RTKs), Cancer Drug Targets, Hemangioblast Markers |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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