Human Dynein Cytoplasmic Light Chain 1 (DYNLL1) has been identified as a protein that interacts with NOS1, leading to NOS1 inhibition. NOS1 dimer is destabilized after binding DYNLL1 a conformation necessary activity, and it regulate numerous biologic processes throughits effects on nitric oxide synthase activity. DYNLL1 is widely expressed, with higher expression in testis and moderate expression in brain.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 μg | 5 days | $ 184.00 | |
50 μg | 5 days | $ 545.00 | |
500 μg | 5 days | $ 1,900.00 | |
1 mg | 5 days | $ 2,730.00 |
Description | Human Dynein Cytoplasmic Light Chain 1 (DYNLL1) has been identified as a protein that interacts with NOS1, leading to NOS1 inhibition. NOS1 dimer is destabilized after binding DYNLL1 a conformation necessary activity, and it regulate numerous biologic processes throughits effects on nitric oxide synthase activity. DYNLL1 is widely expressed, with higher expression in testis and moderate expression in brain. |
Species | Human |
Expression System | E. coli |
Tag | N-6His |
Accession Number | P63167 |
Synonyms | DNCL1, PIN, DLC8, Protein Inhibitor of Neuronal Nitric Oxide Synthase, DNCLC1, DLC1, DYNLL1, Dynein Light Chain LC8-Type 1, 8 kDa Dynein Light Chain, Dynein Light Chain 1 Cytoplasmic, HDLC1 |
Amino Acid | Met1-Gly89 |
Construction | Recombinant Human Cytoplasmic Dynein Light Chain 1 is produced by our E.coli expression system and the target gene encoding Met1-Gly89 is expressed with a 6His tag at the N-terminus. |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
Molecular Weight | 14 KDa, reducing conditions |
Endotoxin | Less than 1 EU/µg as determined by LAL test. |
Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM Histidine-HCl, 10% Trehalose, 0.05% Tween 80, pH6.0. |
Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Stability & Storage |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
Shipping |
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Research Background | Human Dynein Cytoplasmic Light Chain 1 (DYNLL1) has been identified as a protein that interacts with NOS1, leading to NOS1 inhibition. NOS1 dimer is destabilized after binding DYNLL1 a conformation necessary activity, and it regulate numerous biologic processes throughits effects on nitric oxide synthase activity. DYNLL1 is widely expressed, with higher expression in testis and moderate expression in brain. |
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DYNLL1 Protein, Human, Recombinant (His) DNCL1 PIN DLC8 HDLC-1 Protein Inhibitor of Neuronal Nitric Oxide Synthase DNCL-1 HDLC 1 DLC-8 DNCLC1 DLC1 DLC 8 DYNLL1 DNCLC 1 Dynein Light Chain LC8-Type 1 DYNLL 1 8 kDa Dynein Light Chain DNCL 1 Dynein Light Chain 1 Cytoplasmic DYNLL-1 DNCLC-1 DLC-1 HDLC1 DLC 1 recombinant recombinant-proteins proteins protein