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Anti-IL-15 Antibody (5P630)
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Catalog No. TMAY-00689
Alias interleukin 15, IL-15
Anti-IL-15 Antibody (5P630) is a Mouse antibody targeting IL-15. Anti-IL-15 Antibody (5P630) can be used in ELISA.
Anti-IL-15 Antibody (5P630)
Anti-IL-15 Antibody (5P630)
😃Good
Catalog No. TMAY-00689Alias interleukin 15, IL-15
Anti-IL-15 Antibody (5P630) is a Mouse antibody targeting IL-15. Anti-IL-15 Antibody (5P630) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $92 | 7-10 days | |
| 100 μL | $268 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-IL-15 Antibody (5P630) is a Mouse antibody targeting IL-15. Anti-IL-15 Antibody (5P630) can be used in ELISA. |
| Alias | interleukin 15, IL-15 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 5P630 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL-15 / IL15 / Interleukin 15 (rh IL-15 / IL15 / Interleukin 15; TMPY-04049; NP_000576.1; Asn49-Ser162). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in 20 mM MES, 100 mM NaCl, 10% Trehalose, pH 6.0 |
| Research Background | The protein encoded by the IL15 gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietic receptor subunits and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively, spliced transcript variants of this gene have been reported.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human IL-15 / IL15 / Interleukin 15 Protein (TMPY-04049) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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