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Frizzled 4 Protein, Human, Recombinant (hFc)

Catalog No. TMPY-00197
Synonyms: Fz-4, hFz4, EVR1, FEVR, Fz4, GPCR, CD344, FzE4, frizzled class receptor 4, FZD4S

Familial exudative vitreoretinopathy (FEVR) is a hereditary blinding disorder that features defects in retinal vascular development. Mutations in FZD4 are known to cause autosomal dominant exudative vitreoretinopathy (EVR1). The mutations in FZD4 are associated with the phenotypes of retinal folds or ectopic macula in FEVR

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Frizzled 4 Protein, Human, Recombinant (hFc)
Pack Size Availability Price/USD Quantity
50 μg 5 days $ 357.00
500 μg 5 days $ 2,330.00
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Biological Description
Technical Params
Product Properties
Description Familial exudative vitreoretinopathy (FEVR) is a hereditary blinding disorder that features defects in retinal vascular development. Mutations in FZD4 are known to cause autosomal dominant exudative vitreoretinopathy (EVR1). The mutations in FZD4 are associated with the phenotypes of retinal folds or ectopic macula in FEVR
Species Human
Expression System HEK293
Tag hFc
Accession Number Q9ULV1
Synonyms Fz-4, hFz4, EVR1, FEVR, Fz4, GPCR, CD344, FzE4, frizzled class receptor 4, FZD4S
Construction A DNA sequence encoding the human FZD4 (NP_036325.2) (Met1-Glu180) was expressed with the Fc region of human IgG1 at the C-terminus.
Protein Purity > 95 % as determined by SDS-PAGE.
Molecular Weight 43.3 kDa (predicted)
Endotoxin < 1.0 EU per μg protein as determined by the LAL method.
Formulation Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Reconstitution A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background Familial exudative vitreoretinopathy (FEVR) is a hereditary blinding disorder that features defects in retinal vascular development. Mutations in FZD4 are known to cause autosomal dominant exudative vitreoretinopathy (EVR1). The mutations in FZD4 are associated with the phenotypes of retinal folds or ectopic macula in FEVR

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Please read the User Guide of Recombinant Proteins for more specific information.

Keywords

Frizzled 4 Protein, Human, Recombinant (hFc) Fz-4 hFz4 EVR1 FEVR CD 344 EVR-1 Fz4 GPCR CD344 EVR 1 CD-344 FzE4 frizzled class receptor 4 FZD4S recombinant recombinant-proteins proteins protein

 

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