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Anti-ACVR2B Antibody (8P180)
😃Good
Catalog No. TMAY-03158
Alias activin A receptor, type IIB
Anti-ACVR2B Antibody (8P180) is a Rabbit antibody targeting ACVR2B. Anti-ACVR2B Antibody (8P180) can be used in ELISA.
Anti-ACVR2B Antibody (8P180)
Anti-ACVR2B Antibody (8P180)
😃Good
Catalog No. TMAY-03158Alias activin A receptor, type IIB
Anti-ACVR2B Antibody (8P180) is a Rabbit antibody targeting ACVR2B. Anti-ACVR2B Antibody (8P180) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Mouse |
| Alias | activin A receptor, type IIB |
| Ig Type | Rabbit IgG |
| Clone | 8P180 |
| Reactivity | Mouse |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse ACVR2B (rM ACVR2B ; TMPY-01281; NP_031423.1; Met1-Thr134). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of skeletal muscle growth, is regarded as a potential therapeutic target and binds to ACVR2B effectively, and to a lesser extent, to ACVR2A. The structure of human ACVR2B kinase domain in complex with adenine establishes the conserved bilobal architecture consistent with all other catalytic kinase domains. Haplotype structure at the ACVR2B and follistatin loci may contribute to interindividual variation in skeletal muscle mass and strength. Defects in ACVR2B are a cause of left-right axis malformations. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse ACVR2B Protein (TMPY-01281) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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