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MSLN/Mesothelin Protein, Human, Recombinant (hFc), Biotinylated
(Synonyms: SMRP, MPF, mesothelin) Copy Product InfoSynonyms: SMRP, MPF, mesothelin
Catalog No. TMPY-02875 Copy Product Info
Mesothelin Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 60.7 kDa and the accession number is Q13421-2.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $112 | 7-10 days | 7-10 days | |
| 10 µg | $183 | 7-10 days | 7-10 days | |
| 20 µg | $306 | 7-10 days | 7-10 days | |
| 50 µg | $492 | 7-10 days | 7-10 days | |
| 100 µg | $842 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Anti-MSLN Antibody, human IgG1 at 2 μg/mL (100 μL/well) can bind Recombinant Human MSLN/Mesothelin Protein (Fc Tag), Biotinylated (Cat#TMPY-02875), the EC50 is 0.9-2.7 ng/mL. |
| Description | Mesothelin Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 60.7 kDa and the accession number is Q13421-2. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | N-hFc |
| Accession Number | Q13421-2 |
| Construction | A DNA sequence encoding the human MSLN (Q13421-2) (Glu296-Gly580) was expressed with the fused Fc region of human IgG1 at the N-terminus. The expressed protein was biotinylated in vitro. Predicted N terminal: Glu |
| Protein Purity | > 85 % as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Synonyms | SMRP, MPF, mesothelin |
| Research Background | The megakaryocyte potentiating factor belongs to the mesothelin family. This family is comprised of several mammalian pre-pro-megakaryocyte potentiating factor precursor (MPF) or mesothelin proteins. Mesothelin is a glycosylphosphatidylinositol-linked glycoprotein highly expressed in mesothelial cells, mesotheliomas, and ovarian cancer, but the biological function of the protein is not known. Megakaryocyte potentiating factor is highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level). It interacts with MUC16 and potentiates megakaryocyte colony formation in vitro. Megakaryocyte potentiating factor is secreted by several mesothelioma cell lines and is frequently elevated in the blood of patients with mesothelioma. Measurement of this protein may be useful in following the response of mesothelioma to treatment.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Molecular Weight | 60.7 kDa (predicted); 65 kDa (reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: MSLN/Mesothelin Protein, Human, Recombinant (hFc), Biotinylated chemical structure | MSLN/Mesothelin Protein, Human, Recombinant (hFc), Biotinylated molecular weight
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