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4-Chlorophenylurea

Name: 4-Chlorophenylurea
Brand: TargetMol
SKU: T20454
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T20454Cas No. 140-38-5

Alias NSC-12971, NSC12971, NSC 12971

4-Chlorophenylurea (NSC-12971) is a novel orally bioavailable inhibitor of factor Xa.

4-Chlorophenylurea

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Purity: 98.87%

Catalog No. T20454Alias NSC-12971, NSC12971, NSC 12971Cas No. 140-38-5

4-Chlorophenylurea (NSC-12971) is a novel orally bioavailable inhibitor of factor Xa.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$29	-	In Stock
1 mL x 10 mM (in DMSO)	$39	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:98.87%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

4-Chlorophenylurea AI Summary

4-Chlorophenylurea exhibits diverse bioactivities including activation of the NPC1 promoter with a potency of 3981.1 nM, inhibition of T. brucei phosphofructokinase with potencies of 30131.3 nM, 21331.3 nM, and 23934.1 nM, and action as a delayed death inhibitor of the malarial parasite plastid with 96-hour and 48-hour incubation periods, showing potencies of 11689.1 nM and 14715.7 nM, respectively. Additionally, it inhibits Polymerase Iota with a potency of 89125.1 nM and Hepatitis C Virus (HCV) with a potency of 12589.3 nM..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	4-Chlorophenylurea (NSC-12971) is a novel orally bioavailable inhibitor of factor Xa.
Synonyms	NSC-12971, NSC12971, NSC 12971

Chemical Properties

Molecular Weight	170.6
Formula	C₇H₇ClN₂O
Cas No.	140-38-5
Smiles	NC(=O)NC1=CC=C(Cl)C=C1
Relative Density.	1.402g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 65 mg/mL (381.01 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.8617 mL	29.3083 mL	58.6166 mL	293.0832 mL
5 mM	1.1723 mL	5.8617 mL	11.7233 mL	58.6166 mL
10 mM	0.5862 mL	2.9308 mL	5.8617 mL	29.3083 mL
20 mM	0.2931 mL	1.4654 mL	2.9308 mL	14.6542 mL
50 mM	0.1172 mL	0.5862 mL	1.1723 mL	5.8617 mL
100 mM	0.0586 mL	0.2931 mL	0.5862 mL	2.9308 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc