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Anti-Carbonic Anhydrase 12 Antibody (2P389) is a Rabbit antibody targeting Carbonic Anhydrase 12. Anti-Carbonic Anhydrase 12 Antibody (2P389) can be used in ELISA,IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Anti-Carbonic Anhydrase 12 Antibody (2P389) is a Rabbit antibody targeting Carbonic Anhydrase 12. Anti-Carbonic Anhydrase 12 Antibody (2P389) can be used in ELISA,IHC-P. |
Alias | HsT18816, FLJ20151, CAXII, carbonic anhydrase XII, CA12 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 2P389 |
Reactivity | Mouse |
Verified Activity | 1. Immunochemical staining of mouse CA12 in mouse kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of mouse CA12 in mouse intestine with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
Application | ELISA,IHC-P |
Recommended Dose | ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Carbonic Anhydrase XII / CA12 (rM Carbonic Anhydrase XII / CA12; TMPY-00688; NP_848483.2; Met 1-Ser 301). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CA12, also known as Car12 and carbonic anhydrase XII, is a type I membrane enzyme of an N-terminal extracellular catalytic domain, a membrane-spanning α-helix, and a small intracellular C-terminal domain. It is highly expressed in colon, kidney, prostate, intestine and activated lymphocytes and moderately expressed in pancreas, ovary, and testis. Overexpression of the CA12 is observed in certain human cancers and is used as a tumor marker. rmCA12 corresponds to the extracellular domain and has both carbonic anhydrase activity and esterase activity. |
Conjucates | Unconjugated |
Immunogen | Recombinant Mouse Carbonic Anhydrase XII / CA12 Protein (TMPY-00688) |
Antigen Species | Mouse |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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