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IL-12B Protein, Human, Recombinant

Catalog No. TMPJ-00216
Synonyms: Interleukin-12 subunit beta, IL-12B, CLMF p40, NKSF2, Interleukin-12 subunit β, Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL12B, NK cell stimulatory factor chain 2, IL-12 subunit p40

Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. IL-12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor encoded by IL12B and a 35 kD subunit encoded by IL12A. IL12 is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. It has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
IL-12B Protein, Human, Recombinant
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 129.00
50 μg 5 days $ 390.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. IL-12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor encoded by IL12B and a 35 kD subunit encoded by IL12A. IL12 is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. It has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen.
Species Human
Expression System Human Cells
Tag None
Accession Number P29460
Synonyms Interleukin-12 subunit beta, IL-12B, CLMF p40, NKSF2, Interleukin-12 subunit β, Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL12B, NK cell stimulatory factor chain 2, IL-12 subunit p40
Amino Acid Ile23-Ser328
Construction Recombinant Human Interleukin-12 Subunit Beta is produced by our Mammalian expression system and the target gene encoding Ile23-Ser328 is expressed.
Molecular Weight 40-47 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Research Background Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. IL-12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor encoded by IL12B and a 35 kD subunit encoded by IL12A. IL12 is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. It has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen.

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Keywords

IL-12B Protein, Human, Recombinant Interleukin-12 subunit beta IL-12B CLMF p40 NKSF2 Interleukin-12 subunit β Cytotoxic lymphocyte maturation factor 40 kDa subunit NKSF 2 IL12B NK cell stimulatory factor chain 2 NKSF-2 IL-12 subunit p40 recombinant recombinant-proteins proteins protein

 

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