IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi)

IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is Q9NPH3-1.

Pack Size	Availability	Price/USD
100 μg	5 days	$ 207.00
500 μg	5 days	$ 838.00
1 mg	5 days	$ 1,400.00

Pack Size

Availability

Price/USD

Quantity

100 μg

5 days

$ 207.00

500 μg

5 days

$ 838.00

1 mg

5 days

$ 1,400.00

Description

IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is Q9NPH3-1.

Species	Human
Expression System	HEK293 Cells
Tag	C-His-Avi
Accession Number	Q9NPH3-1
Synonyms	C3orf13, IL-1 R3, IL1RAP, IL-1RAP, IL-1 RAcP
Construction	Ser21-Glu359
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight	42 kDa (predicted). Due to glycosylation, the protein migrates to 52-70 kDa based on Tris-Bis PAGE result.

Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	IL-1 Receptor Accessory Protein (IL-1 RAcP), also known as IL-1 R3, is a ubiquitously expressed 70-90 kDa member of the Interleukin-1 receptor family of proteins. It serves as a non-ligand-binding component of the receptors for IL-1 alpha, IL-1 beta, IL-33, and IL-36. IL-1 R3 is a coreceptor for IL1RL2 in the IL-36 signaling system. IL-1 R3 is a coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.