QPRTase Protein, Human, Recombinant (His)

Name: QPRTase Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-00473
Rating: 4.5 (1 reviews)

(Synonyms: Quinolinate Phosphoribosyltransferase [Decarboxylating], QPRTase, QPRT, QAPRTase, Nicotinate-Nucleotide Pyrophosphorylase [Carboxylating]) Copy Product Info

Synonyms: Quinolinate Phosphoribosyltransferase [Decarboxylating], QPRTase, QPRT, QAPRTase, Nicotinate-Nucleotide Pyrophosphorylase [Carboxylating]

Catalog No. TMPJ-00473 Copy Product Info

Nicotinate-Nucleotide Pyrophosphorylase (QPRT) belongs to the nadC/modD family. QPRT plays an improtant role in catabolism of quinolinate which acts as a potent endogenous exitotoxin to neurons. In addition, QPRT serves as an an intermediate in the Tryptophan-Nicotinamide Adenine Dinucleotide pathway. QPRT participates in some pathways including Cofactor biosynthesis, NAD(+) biosynthesis and the Nicotinate D-Ribonucleotide from Quinolinate. In addition, QPRT is involved in the catabolism of Quinolinic Acid (QA). The activity toward QA is slightly repressed by phosphoribosylpyrophosphate (PRPP) in both a competitive and a non-competitive manner.

QPRTase Protein, Human, Recombinant (His)

Customer service consultation

Pack Size	Price	USA Stock	Global Stock
10 µg	$183	6-8 weeks	6-8 weeks
20 µg	$292	6-8 weeks	6-8 weeks
50 µg	$545	6-8 weeks	6-8 weeks
100 µg	$792	6-8 weeks	6-8 weeks
200 µg	$1,150	6-8 weeks	6-8 weeks
500 µg	$1,900	6-8 weeks	6-8 weeks
1 mg	$2,730	6-8 weeks	6-8 weeks

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Resource Download

User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Nicotinate-Nucleotide Pyrophosphorylase (QPRT) belongs to the nadC/modD family. QPRT plays an improtant role in catabolism of quinolinate which acts as a potent endogenous exitotoxin to neurons. In addition, QPRT serves as an an intermediate in the Tryptophan-Nicotinamide Adenine Dinucleotide pathway. QPRT participates in some pathways including Cofactor biosynthesis, NAD(+) biosynthesis and the Nicotinate D-Ribonucleotide from Quinolinate. In addition, QPRT is involved in the catabolism of Quinolinic Acid (QA). The activity toward QA is slightly repressed by phosphoribosylpyrophosphate (PRPP) in both a competitive and a non-competitive manner.
Species	Human
Expression System	E. coli
Tag	N-6xHis
Accession Number	AAH05060.1
Amino Acid	Met1-His297
Construction	Met1-His297
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.
Synonyms	Quinolinate Phosphoribosyltransferase [Decarboxylating], QPRTase, QPRT, QAPRTase, Nicotinate-Nucleotide Pyrophosphorylase [Carboxylating]
Research Background	Nicotinate-Nucleotide Pyrophosphorylase (QPRT) belongs to the nadC/modD family. QPRT plays an improtant role in catabolism of quinolinate which acts as a potent endogenous exitotoxin to neurons. In addition, QPRT serves as an an intermediate in the Tryptophan-Nicotinamide Adenine Dinucleotide pathway. QPRT participates in some pathways including Cofactor biosynthesis, NAD(+) biosynthesis and the Nicotinate D-Ribonucleotide from Quinolinate. In addition, QPRT is involved in the catabolism of Quinolinic Acid (QA). The activity toward QA is slightly repressed by phosphoribosylpyrophosphate (PRPP) in both a competitive and a non-competitive manner.

Chemical Properties

Molecular Weight

34 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.