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Anti-CSF3R/G-CSFR Antibody-PE (4I21)

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Catalog No. TMAY-00481P

Anti-CSF3R/G-CSFR Antibody-PE (4I21) is a PE-conjugated Mouse antibody targeting CSF3R/G-CSFR. Anti-CSF3R/G-CSFR Antibody-PE (4I21) can be used in FCM.

Anti-CSF3R/G-CSFR Antibody-PE (4I21)

Anti-CSF3R/G-CSFR Antibody-PE (4I21)

🥰Excellent
Catalog No. TMAY-00481P
Anti-CSF3R/G-CSFR Antibody-PE (4I21) is a PE-conjugated Mouse antibody targeting CSF3R/G-CSFR. Anti-CSF3R/G-CSFR Antibody-PE (4I21) can be used in FCM.
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Product Introduction

Bioactivity
Description
Anti-CSF3R/G-CSFR Antibody-PE (4I21) is a PE-conjugated Mouse antibody targeting CSF3R/G-CSFR. Anti-CSF3R/G-CSFR Antibody-PE (4I21) can be used in FCM.
Ig Type
Monoclonal Mouse IgG1
Clone
4I21
Reactivity
Human
Verified Activity
Flow cytometric analysis of anti-human GCSFR (CD114) on human whole blood granulocytes. The fluorescence histograms were derived from events with the forward and side light-scatter characteristics of viable granulocytes.
Application
FCM
Recommended Dose
10 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human G-CSFR / CD114 (rh G-CSFR / CD114; NP_000751.1Met 1-Pro 621) and conjugated with PE under optimum conditions, the unreacted PE was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.1% sodium azide
Research BackgroundGranulocyte Colony Stimulating Factor Receptor (G-CSFR), also known as CD114, which belongs to the cytokine receptor superfamily, is a cell surface receptor for colony stimulating factor 3 (CSF3). It is a critical regulator of granulopoiesis. This type I membrane protein has a composite structure consisting of an immunoglobulin(Ig)-like domain, a cytokine receptor-homologous (CRH) domain and three fibronectin type III (FNIII) domains in the extracellular region. Mutations in the G-CSF receptor leading to carboxy-terminal truncation transduce hyperproliferative growth responses, and are implicated in the pathological progression of severe congenital neutropenia (SCN) to acute myelogenous leukemia (AML). Additionally, autocrine/paracrine stimulation of G-CSFR may be important in the biology of solid tumors, including metastasis.
Related Conjugates and Formulations
Conjucates
PE
Others Formats
Unconjugated/APC
Antibody Types Available
3
Antigen Details
Immunogen
Recombinant Human G-CSFR / CD114 protein
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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