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Anti-CSF3R/G-CSFR Antibody-PE (4I21)
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Catalog No. TMAY-00481P
Alias GCSFR, G-CSF R, CSF3R, colony stimulating factor 3 receptor (granulocyte), CD114
Anti-CSF3R/G-CSFR Antibody-PE (4I21) is a PE-conjugated Mouse antibody targeting CSF3R/G-CSFR. Anti-CSF3R/G-CSFR Antibody-PE (4I21) can be used in FCM.
Anti-CSF3R/G-CSFR Antibody-PE (4I21)
Anti-CSF3R/G-CSFR Antibody-PE (4I21)
😃Good
Catalog No. TMAY-00481PAlias GCSFR, G-CSF R, CSF3R, colony stimulating factor 3 receptor (granulocyte), CD114
Anti-CSF3R/G-CSFR Antibody-PE (4I21) is a PE-conjugated Mouse antibody targeting CSF3R/G-CSFR. Anti-CSF3R/G-CSFR Antibody-PE (4I21) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 T | $104 | 7-10 days | |
| 100 T | $329 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: FCM Reactivity: Human |
| Alias | GCSFR, G-CSF R, CSF3R, colony stimulating factor 3 receptor (granulocyte), CD114 |
| Ig Type | Mouse IgG1 |
| Clone | 4I21 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of anti-human GCSFR (CD114) on human whole blood granulocytes. The fluorescence histograms were derived from events with the forward and side light-scatter characteristics of viable granulocytes. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human G-CSFR / CD114 (rh G-CSFR / CD114; NP_000751.1Met 1-Pro 621) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.1% sodium azide |
| Research Background | Granulocyte Colony Stimulating Factor Receptor (G-CSFR), also known as CD114, which belongs to the cytokine receptor superfamily, is a cell surface receptor for colony stimulating factor 3 (CSF3). It is a critical regulator of granulopoiesis. This type I membrane protein has a composite structure consisting of an immunoglobulin(Ig)-like domain, a cytokine receptor-homologous (CRH) domain and three fibronectin type III (FNIII) domains in the extracellular region. Mutations in the G-CSF receptor leading to carboxy-terminal truncation transduce hyperproliferative growth responses, and are implicated in the pathological progression of severe congenital neutropenia (SCN) to acute myelogenous leukemia (AML). Additionally, autocrine/paracrine stimulation of G-CSFR may be important in the biology of solid tumors, including metastasis. |
| Conjucates | PE |
| Others Formats | Unconjugated/APC |
| Antibody Types Available | 3 |
| Immunogen | Recombinant Protein: Human G-CSFR / CD114 protein |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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