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Anti-CD8 alpha Antibody (2Z667)
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Catalog No. TMAY-01401
Alias p32 186910, p32, MAL, Leu-2, Leu2, CD8a molecule, CD8 α, CD8 alpha, CD8
Anti-CD8 alpha Antibody (2Z667) is a Mouse antibody targeting CD8 alpha. Anti-CD8 alpha Antibody (2Z667) can be used in ELISA(Cap).
Anti-CD8 alpha Antibody (2Z667)
Anti-CD8 alpha Antibody (2Z667)
😃Good
Catalog No. TMAY-01401Alias p32 186910, p32, MAL, Leu-2, Leu2, CD8a molecule, CD8 α, CD8 alpha, CD8
Anti-CD8 alpha Antibody (2Z667) is a Mouse antibody targeting CD8 alpha. Anti-CD8 alpha Antibody (2Z667) can be used in ELISA(Cap).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $69 | 7-10 days | |
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
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Antigen Details
Chemical Properties
| Description | Anti-CD8 alpha Antibody (2Z667) is a Mouse antibody targeting CD8 alpha. Anti-CD8 alpha Antibody (2Z667) can be used in ELISA(Cap). |
| Alias | p32 186910, p32, MAL, Leu-2, Leu2, CD8a molecule, CD8 α, CD8 alpha, CD8 |
| Ig Type | Monoclonal mouse IgG1 |
| Clone | 2Z667 |
| Reactivity | Human |
| Application | ELISA(Cap) |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD8 / CD8 alpha / Leu-2 (rh CD8 / CD8 alpha / Leu-2; NP_001759.3Met1-Asp182). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been implicated in the recognition of monomorphic determinants on major histocompatibility complex (MHC) Class I antigens, and in signal transduction during the course of T-cell activation. Both human and rodent CD8 antigens are comprised of two distinct polypeptide chains, alpha and beta. The Ig domains of CD8 alpha are involved in controlling the ability of CD8 to be expressed. Mutation of B- and F-strand cysteine residues in CD8 alpha reduced the ability of the protein to fold properly and, therefore, to be expressed. Defects in CD8A are a cause of familial CD8 deficiency. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human CD8 / CD8 alpha / Leu-2 Protein |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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