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PDGFR Tyrosine Kinase Inhibitor III

🥰Excellent
Catalog No. T60108Cas No. 205254-94-0
Alias PDGF Receptor Tyrosine Kinase Inhibitor III

PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III) is a multikinase inhibitor that inhibits PDGFR, EGFR, FGFR, PKA, and PKC and can be used for research on amyotrophic lateral sclerosis [1].

PDGFR Tyrosine Kinase Inhibitor III

PDGFR Tyrosine Kinase Inhibitor III

🥰Excellent
Purity: 99.50%
Catalog No. T60108Alias PDGF Receptor Tyrosine Kinase Inhibitor IIICas No. 205254-94-0
PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III) is a multikinase inhibitor that inhibits PDGFR, EGFR, FGFR, PKA, and PKC and can be used for research on amyotrophic lateral sclerosis [1].
Pack SizePriceAvailabilityQuantity
5 mg$44In Stock
10 mg$71In Stock
25 mg$163In Stock
50 mg$237In Stock
100 mg$343In Stock
200 mg$469In Stock
1 mL x 10 mM (in DMSO)$46In Stock
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Purity:99.50%
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Product Introduction

Bioactivity
Description
PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III) is a multikinase inhibitor that inhibits PDGFR, EGFR, FGFR, PKA, and PKC and can be used for research on amyotrophic lateral sclerosis [1].
SynonymsPDGF Receptor Tyrosine Kinase Inhibitor III
Chemical Properties
Molecular Weight485.53
FormulaC27H27N5O4
Cas No.205254-94-0
SmilesO(C)C1=CC=2C(=NC=NC2C=C1OC)N3CCN(C(NC4=CC=C(OC5=CC=CC=C5)C=C4)=O)CC3
Relative Density.1.310 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (102.98 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0596 mL10.2980 mL20.5960 mL102.9802 mL
5 mM0.4119 mL2.0596 mL4.1192 mL20.5960 mL
10 mM0.2060 mL1.0298 mL2.0596 mL10.2980 mL
20 mM0.1030 mL0.5149 mL1.0298 mL5.1490 mL
50 mM0.0412 mL0.2060 mL0.4119 mL2.0596 mL
100 mM0.0206 mL0.1030 mL0.2060 mL1.0298 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

PDGFR Tyrosine Kinase Inhibitor IIIPDGFR
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