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Poneratoxin acetate

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Catalog No. TP3045

Poneratoxin acetate is a neurotoxic peptide and modulator of NaV1.6/NaV1.7, lowering the activation threshold of voltage-gated sodium channels and causing pain.

Poneratoxin acetate

Poneratoxin acetate

😃Good
Catalog No. TP3045
Poneratoxin acetate is a neurotoxic peptide and modulator of NaV1.6/NaV1.7, lowering the activation threshold of voltage-gated sodium channels and causing pain.
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1 mg$44In Stock
5 mgPreferential7-10 days
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Product Introduction

Bioactivity
Description
Poneratoxin acetate is a neurotoxic peptide and modulator of NaV1.6/NaV1.7, lowering the activation threshold of voltage-gated sodium channels and causing pain.
Chemical Properties
Molecular Weight2756.35 (free base)
FormulaC129H215N33O31S.xC2H4O2
Smiles[H]N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N2CCC[C@H]2C(N[C@H](C(N[C@H](C(N[C@]([H])(C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCSC)C(N[C@]([H])(C(N3CCC[C@H]3C(N4CCC[C@H]4C(N[C@H](C(N[C@]([H])(C(N[C@H](C(N[C@@H](C)C(N[C@]([H])(C(N[C@@H](CC5=CN=CN5)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N[C@H](C(N[C@H](C(N)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)=O)=O)=O)[C@@H](C)CC)=O)=O)CCC(N)=O)=O)[C@@H](C)CC)=O)C(C)C)=O)=O)=O)[C@H](O)C)=O)=O)CC(C)C)=O)CC(C)C)=O)CO)=O)=O)CC(C)C)=O)[C@@H](C)CC)=O)CC(C)C)=O)CC(C)C)=O)=O)CC(C)C)=O.CC(O)=O
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 120 mg/mL, Sonication is recommended.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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