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Anti-Phospho-EPOR (Tyr368) Polyclonal Antibody is a Rabbit antibody targeting Phospho-EPOR (Tyr368). Anti-Phospho-EPOR (Tyr368) Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $218 | 7-10 days | 7-10 days | |
| 100 μL | $318 | 7-10 days | 7-10 days |
| Description | Anti-Phospho-EPOR (Tyr368) Polyclonal Antibody is a Rabbit antibody targeting Phospho-EPOR (Tyr368). Anti-Phospho-EPOR (Tyr368) Polyclonal Antibody can be used in WB. |
| Synonyms | p-EPOR (Y368), p-EPOR (Tyr368), EPOR (p-Y368), EPOR (p-Tyr368) |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Western blot analysis of extracts from K562 tissue using Epo-R (Phospho-Tyr368) antibody TMAC-01343.The lane on the right is treated with the antigen-specific peptide. ![]() |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of Tyrosine 368 (D-T-Y(p)-L-V) derived from Human Epo-R |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 55 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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