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IL-18RAP Protein, Human, Recombinant (hFc & His)
(Synonyms: Interleukin-18 receptor β, Interleukin-18 receptor beta, Interleukin-18 receptor accessory protein-like, Interleukin-18 receptor accessory protein, Interleukin-1 receptor 7, IL-1R accessory protein-like, IL18RAP, CDw218b, CD218 antigen-like family member B, C, Accessory protein-like) Copy Product InfoSynonyms: Interleukin-18 receptor β, Interleukin-18 receptor beta, Interleukin-18 receptor accessory protein-like, Interleukin-18 receptor accessory protein, Interleukin-1 receptor 7, IL-1R accessory protein-like, IL18RAP, CDw218b, CD218 antigen-like family member B, C, Accessory protein-like
Catalog No. TMPJ-00344 Copy Product Info
IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $39 | 35 days | 35 days | |
| 10 μg | $60 | 35 days | 35 days | |
| 20 μg | $96 | 35 days | 35 days | |
| 50 μg | $183 | 35 days | 35 days | |
| 100 μg | $332 | 35 days | 35 days | |
| 200 μg | $592 | 35 days | 35 days | |
| 500 μg | $1,350 | 35 days | 35 days | |
| 1 mg | $2,010 | 35 days | 35 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc-6xHis |
| Accession Number | O95256 |
| Amino Acid | Phe20-Arg356 |
| Construction | Phe20-Arg356 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | Interleukin-18 receptor β, Interleukin-18 receptor beta, Interleukin-18 receptor accessory protein-like, Interleukin-18 receptor accessory protein, Interleukin-1 receptor 7, IL-1R accessory protein-like, IL18RAP, CDw218b, CD218 antigen-like family member B, C, Accessory protein-like |
| Research Background |
| Molecular Weight | 88 KDa (reducing condition) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: IL-18RAP Protein, Human, Recombinant (hFc & His) chemical structure | IL-18RAP Protein, Human, Recombinant (hFc & His) molecular weight
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