IL-18RAP Protein, Human, Recombinant (hFc & His)

Catalog No. TMPJ-00344

IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.

IL-18RAP Protein, Human, Recombinant (hFc & His)

Catalog No. TMPJ-00344

Pack Size	Price	USA Warehouse	Global Warehouse
5 μg	$39	7-10 days	7-10 days
10 μg	$60	7-10 days	7-10 days
20 μg	$96	7-10 days	7-10 days
50 μg	$183	7-10 days	7-10 days
100 μg	$332	7-10 days	7-10 days
200 μg	$592	7-10 days	7-10 days
500 μg	$1,350	7-10 days	7-10 days
1 mg	$2,010	7-10 days	7-10 days

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In Stock Estimated shipping dateUSA Warehouse [1-2 days] Global Warehouse [5-7 days]

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Product Information

Biological Activity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc-6xHis
Accession Number	O95256
Synonyms	Interleukin-18 receptor β,Interleukin-18 receptor beta,Interleukin-18 receptor accessory protein-like,Interleukin-18 receptor accessory protein,Interleukin-1 receptor 7,IL-1R accessory protein-like,IL18RAP,CDw218b,CD218 antigen-like family member B,C,Accessory protein-like
Amino Acid	Phe20-Arg356
Construction	Phe20-Arg356
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight	88 KDa (reducing condition)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background	IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.

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