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Lepidiline A

Name: Lepidiline A
Brand: TargetMol
SKU: T25664
Price: 45 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T25664Cas No. 596093-98-0

Alias Macaline A

Lepidiline A (Macaline A) is a flavonoid lignin with anti-inflammatory activity. Lepidiline A showed cytotoxic activity against HL-60 cells with IC50 of 32.3 μM. It is the active ingredient of Lepidium meyenii Walpers, a plant in the brassica family, and improves the balance of endogenous sex hormones in mice and the fectility of fruit flies. Lepidiline A targets HSD17B1 gene to enhance enzyme activity, improve the efficiency of sex hormone bioconversion, and improve reproductive ability. Lepidiline A has anticancer activity.

Lepidiline A

🥰Excellent

Purity: 99.7%

Catalog No. T25664Alias Macaline ACas No. 596093-98-0

Pack Size	Price	Availability
1 mg	$45	In Stock
5 mg	$106	In Stock
10 mg	$189	In Stock
25 mg	$372	In Stock
50 mg	$546	In Stock
100 mg	$768	In Stock

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Purity:99.7%

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Product Introduction

Bioactivity

Description	Lepidiline A (Macaline A) is a flavonoid lignin with anti-inflammatory activity. Lepidiline A showed cytotoxic activity against HL-60 cells with IC50 of 32.3 μM. It is the active ingredient of Lepidium meyenii Walpers, a plant in the brassica family, and improves the balance of endogenous sex hormones in mice and the fectility of fruit flies. Lepidiline A targets HSD17B1 gene to enhance enzyme activity, improve the efficiency of sex hormone bioconversion, and improve reproductive ability. Lepidiline A has anticancer activity.
Targets&IC50	Cytotoxic activity (HL-60 cells):32.3 μM
Synonyms	Macaline A

Chemical Properties

Molecular Weight	312.84
Formula	C₁₉H₂₁ClN₂
Cas No.	596093-98-0
Smiles	[Cl-].Cc1c(C)[n+](Cc2ccccc2)cn1Cc1ccccc1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (143.84 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1965 mL	15.9826 mL	31.9652 mL	159.8261 mL
5 mM	0.6393 mL	3.1965 mL	6.3930 mL	31.9652 mL
10 mM	0.3197 mL	1.5983 mL	3.1965 mL	15.9826 mL
20 mM	0.1598 mL	0.7991 mL	1.5983 mL	7.9913 mL
50 mM	0.0639 mL	0.3197 mL	0.6393 mL	3.1965 mL
100 mM	0.0320 mL	0.1598 mL	0.3197 mL	1.5983 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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