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Anti-PCNA Antibody (6A447) is a Mouse antibody targeting PCNA. Anti-PCNA Antibody (6A447) can be used in WB,IHC.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $218 | 7-10 days | |
100 μL | $317 | 7-10 days |
Description | Anti-PCNA Antibody (6A447) is a Mouse antibody targeting PCNA. Anti-PCNA Antibody (6A447) can be used in WB,IHC. |
Reactivity | Human,Mouse,Rat |
Application | |
Recommended Dose | WB: 1:3000-10000; IHC: 1:200 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | Hybridoma Monoclonal Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Mouse IgG1 in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | PCNA is a marker for cells in early G1 phase and S phase of the cell cycle. It is found in the nucleus and is a cofactor of DNA polymerase delta. PCNA acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, PCNA is ubiquitinated and is involved in the RAD6 dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for PCNA. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. |
Conjucates | Unconjugated |
Immunogen | A synthesized peptide |
Antigen Species | mouse |
Uniprot ID |
Molecular Weight | Actual: 29 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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