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Anti-HSV1 gD Polyclonal Antibody (Synonyms: US6, HSV1 glycoprotein D, Herpes simplex virus type 1 glycoprotein...)
Catalog No. TMAB-00899 Copy Product Info
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Anti-HSV1 gD Polyclonal Antibody is a Rabbit antibody targeting HSV1 gD. Anti-HSV1 gD Polyclonal Antibody can be used in ELISA,ICC/IF,IF,IHC-Fr,IHC-P,WB.
Anti-HSV1 gD Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-00899
Synonyms US6, HSV1 glycoprotein D, Herpes simplex virus type 1 glycoprotein D, Glycoprotein D, GD_HHV1A, GD
Anti-HSV1 gD Polyclonal Antibody is a Rabbit antibody targeting HSV1 gD. Anti-HSV1 gD Polyclonal Antibody can be used in ELISA,ICC/IF,IF,IHC-Fr,IHC-P,WB.
Anti-HSV1 gD Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-HSV1 gD Polyclonal Antibody is a Rabbit antibody targeting HSV1 gD. Anti-HSV1 gD Polyclonal Antibody can be used in ELISA,ICC/IF,IF,IHC-Fr,IHC-P,WB. |
| Synonyms | US6, HSV1 glycoprotein D, Herpes simplex virus type 1 glycoprotein D, Glycoprotein D, GD_HHV1A, GD |
| Ig Type | IgG |
| Reactivity | (predicted:Herpes Simplex Virus) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Host cytoplasm. Host nucleus, host nucleolus. Virion. Note=At early times in infection, colocalizes with PCNA and replication proteins in cell nuclei, before accumulating in the cytoplasm by 8 to 12 hours post-infection. The effects on the host cell are mediated by de novo-synthesized ICP34.5, the virion-derived population being either non-functional or present in very low amounts. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Herpes simplex type 1 (HSV-1) belongs to a family that includes HSV-2, Epstein-Barr virus (EBV) and Varicella zoster (chicken pox) virus amongst others. HSV-1 and HSV-2 are extremely difficult to distinguish from each other. Members of this family have a characteristic virion structure. The double stranded DNA genome is contained within an icosahedral capsid embedded in a proteinaceous layer (tegument) and surrounded by a lipid envelope, derived from the nuclear membrane of the last host, which is decorated with virus-specific glycoproteins spikes. These viruses are capable of entering a latent phase where the host shows no visible sign of infection and levels of infectious agent become very low. During the latent phase the viral DNA is integrated into the genome of the host cell. |
| Immunogen | KLH conjugated synthetic peptide: HSV1 gD, strain Angelotti |
| Gene Name | RL1 |
| Protein Name | Neurovirulence factor ICP34.5 |
| Biology Area | Cell division,Tumor biomarkers,Other cell division antibodies,DNA Synthesis,Energy Metabolism,Tumor Associated |
| Function | Contributes to HSV resistance to the antiviral effects of alpha/beta interferon. Recruits the serine/threonine-protein phosphatase PPP1CA/PP1-alpha to dephosphorylate the translation initiation factor eIF-2A, thereby couteracting the host shutoff of protein synthesis involving double-stranded RNA-dependent protein kinase EIF2AK2/PKR. Also down-modulates the host MHC class II proteins cell surface expression. Acts as a neurovirulence factor that has a profound effect on the growth of the virus in central nervous system tissue, probably through its ability to maintain an environment favorable for viral replication. |
| Molecular Weight | Theoretical: 41 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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